Hybrid retrosynthesis: organic synthesis using Reaxys and SciFinder

Designed to supplement existing organic textbooks, Hybrid Retrosynthesis presents a relatively simple approach to solving synthesis problems, using a small library of basic reactions along with the computer searching capabilities of Reaxys and SciFinder. This clear, concise guide reviews the essential skills needed for organic synthesis and retrosynthesis, expanding reader knowledge of the foundational principles of these techniques, whilst supporting their use via practical methodologies. Perfect for both graduate and post-graduate students, Hybrid Retrosynthesis provides new applied skills and tools to help during their organic synthesis courses and future careers, whilst simultaneously acting as useful resource for those setting tutorial and group problems, and as a helpful go-to guide for organic chemists involved in either industry or academia.

1. Disconnections and Synthesis2. Making Carbon-Carbon Bonds3. Computer Assisted Syntheses4. A Hybrid Retrosynthesis Approach 5. Searching for Reagents 6. Stereochemistry7. Molecules of Greater Complexity8. Common Fundamental Reactions in Organic Chemistry