KIF2C

KIF2C
Strwythurau PDB Human UniProt search:PDBeRCSB Rhestr o ddynodwyr PDB 2HEH,4UBF,4Y05
Dynodwyr
Cyfenwau	KIF2C,CT139, KNSL6, MCAK, kinesin family member 2C
Dynodwyr allanol	OMIM:604538HomoloGene:21355GeneCards:KIF2C
PatrwmRNApattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd •nucleotide binding •microtubule binding •microtubule plus-end binding •centromeric DNA binding •ATPase activity •GO:0001948, GO:0016582 protein binding •ATP binding •microtubule motor activity Cydrannau o'r gell •cytoplasm •bilen •kinesin complex •microtubule cytoskeleton •Cromosom •microtubule plus-end •cytoplasmic microtubule •chromosome, centromeric region •Cytosgerbwd •microtubule •cnewyllyn cell •kinetochore •nucleoplasm •centrosome •cytosol Prosesau biolegol •antigen processing and presentation of exogenous peptide antigen via MHC class II •establishment or maintenance of microtubule cytoskeleton polarity •chromosome segregation •Cellraniad •regulation of chromosome segregation •microtubule-based movement •cell cycle •microtubule depolymerization •mitotic metaphase plate congression •cell population proliferation •retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum •sister chromatid cohesion •metaphase plate congression •attachment of mitotic spindle microtubules to kinetochore •GO:0007067 Mitosis Sources:Amigo/QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	11004	n/a
Ensembl	ENSG00000142945	n/a
UniProt	Q99661	n/a
RefSeq (mRNA)	NM_001297655 NM_001297656 NM_001297657 NM_006845	n/a
RefSeq (protein)	NP_001284584 NP_001284585 NP_001284586 NP_006836	n/a
Lleoliad (UCSC)	n/a	n/a
PubMedsearch		n/a
Wicidata
Gweld/Golygu Bod dynol

Proteinsy'n cael ei godio yn ycorff dynolgan y genynKIF2CywKIF2Ca elwir hefyd ynKinesin-like protein KIF2C a Kinesin family member 2C(Saesneg). Segment oDNAyw'rgenyn,sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p34.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn KIF2C.

• MCAK
• CT139
• KNSL6

Llyfryddiaeth

• "Functional analysis of phosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cells.".Cell Cycle.2015.PMID26148251.
• "New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C.".J Biol Chem.2015.PMID26055718.
• "MCAK-mediated regulation of endothelial cell microtubule dynamics is mechanosensitive to myosin-II contractility.".Mol Biol Cell.2017.PMID28298485.
• "The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition.".Open Biol.2016.PMID27733589.
• "Molecular insight into the regulation and function of MCAK.".Crit Rev Biochem Mol Biol.2015.PMID27146484.