SCARB2

SCARB2
Strwythurau PDB Human UniProt search:PDBeRCSB Rhestr o ddynodwyr PDB 4F7B,4Q4B,4Q4F,4TVZ,4TW0,4TW2
Dynodwyr
Cyfenwau	SCARB2,AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII, scavenger receptor class B member 2
Dynodwyr allanol	OMIM:602257HomoloGene:48353GeneCards:SCARB2
PatrwmRNApattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd •enzyme binding •GO:0001948, GO:0016582 protein binding •virus receptor activity •phosphatidylserine binding •transmembrane signaling receptor activity •scavenger receptor activity •phospholipid transporter activity •cholesterol binding •phosphatidylcholine binding •protein homodimerization activity •chaperone binding •cargo receptor activity Cydrannau o'r gell •integral component of membrane •lysosome •lysosomal lumen •extracellular exosome •bilen •focal adhesion •lysosomal membrane •Cellbilen •clathrin-coated vesicle membrane •late endosome membrane •Golgi membrane •endoplasmic reticulum membrane •endosome membrane •endocytic vesicle membrane Prosesau biolegol •viral entry into host cell •protein targeting to lysosome •GO:0022415 viral process •positive regulation of neuron projection development •membrane organization •regulation of endosome organization •regulation of glucosylceramidase activity •regulation of lysosome organization •receptor-mediated endocytosis •aminophospholipid transport •regulation of cellular carbohydrate catabolic process Sources:Amigo/QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	950	n/a
Ensembl	ENSG00000138760	n/a
UniProt	Q14108	n/a
RefSeq (mRNA)	NM_005506 NM_001204255	n/a
RefSeq (protein)	NP_001191184 NP_005497	n/a
Lleoliad (UCSC)	n/a	n/a
PubMedsearch		n/a
Wicidata
Gweld/Golygu Bod dynol

Proteinsy'n cael ei godio yn ycorff dynolgan y genynSCARB2ywSCARB2a elwir hefyd ynScavenger receptor class B member 2(Saesneg). Segment oDNAyw'rgenyn,sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SCARB2.

• AMRF
• EPM4
• LGP85
• CD36L2
• HLGP85
• LIMP-2
• LIMPII
• SR-BII

Llyfryddiaeth

• "The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection.".Protein Cell.2017.PMID28447294.
• "SCARB2/LIMP2 deficiency in action myoclonus-renal failure syndrome.".Epileptic Disord.2016.PMID27582254.
• "Changes in the expression of LIMP-2 during cerulein-induced pancreatitis in rats: Effect of inhibition of leukocyte infiltration, cAMP and MAPKs early on in its development.".Int J Biochem Cell Biol.2016.PMID26794464.
• Action Myoclonus - Renal Failure Syndrome.1993.PMID26677510.
• "Increased expression of lysosome membrane protein 2 in glomeruli of patients with idiopathic membranous nephropathy.".Proteomics.2015.PMID26304790.