CSF3

CSF3
Strwythurau PDB Human UniProt search:PDBeRCSB Rhestr o ddynodwyr PDB 2D9Q,1CD9,1GNC,1PGR,1RHG
Dynodwyr
Cyfenwau	CSF3,C17orf33, CSF3OS, GCSF, colony stimulating factor 3
Dynodwyr allanol	OMIM:138970HomoloGene:7677GeneCards:CSF3
PatrwmRNApattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd •cytokine activity •enzyme binding •growth factor activity •granulocyte colony-stimulating factor receptor binding Cydrannau o'r gell •extracellular region •extracellular space Prosesau biolegol •positive regulation of protein kinase B signaling •positive regulation of actin filament polymerization •cellular response to cytokine stimulus •positive regulation of peptidyl-serine phosphorylation •multicellular organism development •granulocyte differentiation •GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response •positive regulation of peptidyl-tyrosine phosphorylation •positive regulation of phosphatidylinositol 3-kinase signaling •positive regulation of protein binding •cellular response to lipopolysaccharide •positive regulation of actin cytoskeleton reorganization •GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II •negative regulation of neuron death •positive regulation of myeloid cell differentiation •response to ethanol •positive regulation of cell population proliferation •neutrophil differentiation •macrophage differentiation •myeloid cell development •regulation of signaling receptor activity •cytokine-mediated signaling pathway •positive regulation of DNA-binding transcription factor activity Sources:Amigo/QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1440	n/a
Ensembl	ENSG00000108342	n/a
UniProt	P09919	n/a
RefSeq (mRNA)	NM_000759 NM_001178147 NM_172219 NM_172220	n/a
RefSeq (protein)	NP_000750 NP_001171618 NP_757373 NP_757374	n/a
Lleoliad (UCSC)	n/a	n/a
PubMedsearch		n/a
Wicidata
Gweld/Golygu Bod dynol

Proteinsy'n cael ei godio yn ycorff dynolgan y genynCSF3ywCSF3a elwir hefyd ynColony stimulating factor 3(Saesneg). Segment oDNAyw'rgenyn,sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CSF3.

• GCSF
• CSF3OS
• C17orf33

Llyfryddiaeth

• "Granulocyte colony-stimulating factor decreases the Th1/Th2 ratio in peripheral blood mononuclear cells from patients with chronic immune thrombocytopenic purpura in vitro.".Thromb Res.2016.PMID27815970.
• "Keratinocyte-Releasable Factors Stimulate the Expression of Granulocyte Colony-Stimulating Factor in Human Dermal Fibroblasts.".J Cell Biochem.2017.PMID27340768.
• "Effect of Granulocyte-Colony Stimulating Factor on Endothelial Cells and Osteoblasts.".Biomed Res Int.2016.PMID27006951.
• "Granulocyte colony-stimulating factor impairs CD8(+) T cell functionality by interfering with central activation elements.".Clin Exp Immunol.2016.PMID26990855.
• "The significance of G-CSF expression and myeloid-derived suppressor cells in the chemoresistance of uterine cervical cancer.".Sci Rep.2015.PMID26666576.