DDT

DDT
Strwythurau PDB Human UniProt search:PDBeRCSB Rhestr o ddynodwyr PDB 4Q3F,3KAN,1DPT
Dynodwyr
Cyfenwau	DDT,DDCT, D-dopachrome tautomerase, MIF-2, MIF2, D-DT
Dynodwyr allanol	OMIM:602750HomoloGene:1038GeneCards:DDT
PatrwmRNApattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd •dopachrome isomerase activity •D-dopachrome decarboxylase activity •lyase activity •GO:0005145 cytokine receptor binding •phenylpyruvate tautomerase activity Cydrannau o'r gell •cytoplasm •extracellular exosome •extracellular space Prosesau biolegol •melanin biosynthetic process •negative regulation of macrophage chemotaxis •positive regulation of tumor necrosis factor production •positive regulation of inflammatory response •positive regulation of ERK1 and ERK2 cascade Sources:Amigo/QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1652	n/a
Ensembl	ENSG00000099977 ENSG00000275003	n/a
UniProt	P30046	n/a
RefSeq (mRNA)	NM_001084392 NM_001355 NM_001381852 NM_001397485	n/a
RefSeq (protein)	NP_001077861 NP_001346 NP_001368781	n/a
Lleoliad (UCSC)	n/a	n/a
PubMedsearch		n/a
Wicidata
Gweld/Golygu Bod dynol

Proteinsy'n cael ei godio yn ycorff dynolgan y genynDDTywDDTa elwir hefyd ynD-dopachrome tautomerase(Saesneg). Segment oDNAyw'rgenyn,sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q11.23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DDT.

• DDCT

Llyfryddiaeth

• "D-dopachrome tautomerase promotes IL-6 expression and inhibits adipogenesis in preadipocytes.".Cytokine.2012.PMID22951300.
• "The action of D-dopachrome tautomerase as an adipokine in adipocyte lipid metabolism.".PLoS One.2012.PMID22428043.
• "UVB-induced inflammation gives increased d-dopachrome tautomerase activity in blister fluid which correlates with macrophage migration inhibitory factor.".Exp Dermatol.2003.PMID12823441.
• "D-dopachrome tautomerase is over-expressed in pancreatic ductal adenocarcinoma and acts cooperatively with macrophage migration inhibitory factor to promote cancer growth.".Int J Cancer.2016.PMID27434219.
• "The clinical significance of the MIF homolog d-dopachrome tautomerase (MIF-2) and its circulating receptor (sCD74) in burn.".Burns.2016.PMID27209369.