EFNB2

EFNB2
Strwythurau PDB Human UniProt search:PDBeRCSB Rhestr o ddynodwyr PDB 2HLE,2I85,2VSK,2VSM,2WO2,3GXU,4UF7
Dynodwyr
Cyfenwau	EFNB2,EPLG5, HTKL, Htk-L, LERK5, ephrin B2
Dynodwyr allanol	OMIM:600527HomoloGene:3019GeneCards:EFNB2
PatrwmRNApattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd •virus receptor activity •GO:0001948, GO:0016582 protein binding •signaling receptor binding •ephrin receptor binding •protein tyrosine kinase activity Cydrannau o'r gell •integral component of membrane •bilen •focal adhesion •Cellbilen •integral component of plasma membrane •Schaffer collateral - CA1 synapse •glutamatergic synapse •integral component of presynaptic membrane •integral component of postsynaptic density membrane Prosesau biolegol •cell differentiation •blood vessel morphogenesis •negative regulation of keratinocyte proliferation •regulation of chemotaxis •cell-cell signaling •anatomical structure morphogenesis •T cell costimulation •lymph vessel development •nervous system development •cell migration involved in sprouting angiogenesis •multicellular organism development •cell adhesion •nephric duct morphogenesis •angiogenesis •animal organ morphogenesis •viral entry into host cell •positive regulation of cardiac muscle cell differentiation •GO:0022415 viral process •venous blood vessel morphogenesis •positive regulation of aorta morphogenesis •positive regulation of cell population proliferation •ephrin receptor signaling pathway •axon guidance •negative regulation of neuron projection development •peptidyl-tyrosine phosphorylation •presynapse assembly •regulation of postsynaptic membrane neurotransmitter receptor levels •regulation of postsynaptic neurotransmitter receptor internalization •positive regulation of neuron death Sources:Amigo/QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1948	n/a
Ensembl	ENSG00000125266	n/a
UniProt	P52799	n/a
RefSeq (mRNA)	NM_004093 NM_001372056 NM_001372057 NM_001372058	n/a
RefSeq (protein)	NP_004084 NP_001358985 NP_001358986 NP_001358987	n/a
Lleoliad (UCSC)	n/a	n/a
PubMedsearch		n/a
Wicidata
Gweld/Golygu Bod dynol

Proteinsy'n cael ei godio yn ycorff dynolgan y genynEFNB2ywEFNB2a elwir hefyd ynEphrin B2(Saesneg). Segment oDNAyw'rgenyn,sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 13, band 13q33.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EFNB2.

• HTKL
• EPLG5
• Htk-L
• LERK5

Llyfryddiaeth

• "Ephrin-B2 reverse signaling regulates progression and lymph node metastasis of oral squamous cell carcinoma.".PLoS One.2017.PMID29190834.
• "Ephrin-B2 overexpression predicts for poor prognosis and response to therapy in solid tumors.".Mol Carcinog.2017.PMID27649287.
• "EphrinB2 Stabilizes Vascularlike Structures Generated by Endothelial Cells and Stem Cells from Apical Papilla.".J Endod.2016.PMID27451120.
• "EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells.".Elife.2016.PMID27350048.
• "DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53.".Cell Death Differ.2016.PMID26494468.