Difebarbamate

Difebarbamate
Clinical data
Routes of; administration	Oral
ATC code	None;
Identifiers
	IUPAC name (5-ethyl-2,4,6-trioxo-5-phenyldihydropyrimidine-1,3(2H,4H)-diyl)bis-3-butoxypropane-1,2-diyl dicarbamate;
CAS Number	15687-09-9;
PubChemCID	71880;
ChemSpider	64896;
UNII	7EE4K616KK;
ChEMBL	ChEMBL2105563;
CompTox Dashboard(EPA)	DTXSID00864624;
ECHA InfoCard	100.036.147
Chemical and physical data
Formula	C28H42N4O9
Molar mass	578.663g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1N(C(=O)N(C(=O)C1(c2ccccc2)CC)CC(OC(=O)N)COCCCC)CC(OC(=O)N)COCCCC;
	InChI InChI=1S/C28H42N4O9/c1-4-7-14-38-18-21(40-25(29)35)16-31-23(33)28(6-3,20-12-10-9-11-13-20)24(34)32(27(31)37)17-22(41-26(30)36)19-39-15-8-5-2/h9-13,21-22H,4-8,14-19H2,1-3H3,(H2,29,35)(H2,30,36); Key:GJJRIOLBUILIGK-UHFFFAOYSA-N;

Difebarbamate(INN) is atranquilizerof thebarbiturateandcarbamatefamilies which is used inEuropeas a component of acombination drug formulationreferred to astetrabamate(Atrium,Sevrium).^[1]^[2]^[3]

References

^Index nominum 2000: international drug directory.Taylor & Francis US. 2000. p. 333.ISBN 978-3-88763-075-1.Retrieved26 November2011.
^World Health Organization (2004)."The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substance"(PDF).
^Vachta J, Valter K, Siegfried B (1990). "Metabolism of difebarbamate in man".European Journal of Drug Metabolism and Pharmacokinetics.15(3): 191–8.doi:10.1007/BF03190203.PMID 2253648.S2CID 2916646.

Clinical data

Routes of administration	Oral
ATC code	None
Identifiers
IUPAC name (5-ethyl-2,4,6-trioxo-5-phenyldihydropyrimidine-1,3(2H,4H)-diyl)bis-3-butoxypropane-1,2-diyl dicarbamate
CAS Number	15687-09-9
PubChemCID	71880
ChemSpider	64896
UNII	7EE4K616KK
ChEMBL	ChEMBL2105563
CompTox Dashboard(EPA)	DTXSID00864624
ECHA InfoCard	100.036.147
Chemical and physical data
Formula	C₂₈H₄₂N₄O₉
Molar mass	578.663g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C1N(C(=O)N(C(=O)C1(c2ccccc2)CC)CC(OC(=O)N)COCCCC)CC(OC(=O)N)COCCCC
InChI InChI=1S/C28H42N4O9/c1-4-7-14-38-18-21(40-25(29)35)16-31-23(33)28(6-3,20-12-10-9-11-13-20)24(34)32(27(31)37)17-22(41-26(30)36)19-39-15-8-5-2/h9-13,21-22H,4-8,14-19H2,1-3H3,(H2,29,35)(H2,30,36) Key:GJJRIOLBUILIGK-UHFFFAOYSA-N