Clavaviridaeis a family of double-stranded viruses that infectarchaea.This family was first described by the team led by D.Prangishviliin 2010.[1]There is one genus in this family (Clavavirus). Within this genus, a single species has been described to date:Aeropyrum pernix bacilliform virus 1(APBV1).[2]
| Clavavirus | |
|---|---|
| |
| Aeropyrum pernix bacilliform virus 1(APBV1) | |
Virus classification
| |
| (unranked): | Virus |
| Family: | Clavaviridae |
| Genus: | Clavavirus |
| Species | |
| |
The name is derived from theLatinwordclava,meaningcudgel,and referring to the thick, stick-like nature of the virus.[3]
Virology
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The virons are bacilliform in shape and 143 nanometers (nm) in length and 15.8 nm in diameter.[1][4]One end is pointed and the other is rounded. The structure of the APBV1 virion has been solved by cryo-electron microscopy to near-atomic resolution, revealing how the helical particle is built from analpha-helicalmajorcapsidprotein with a unique structural fold.[4]Virions are highly thermostable and remain infectious after incubation at 100 °C for 3 hours.[2]
The genome is a circular double-stranded DNA molecule of 5.3 kb. It does not integrate into the host genome. The genome contains 14 open reading frames, none of which share similarity with sequences in public databases.[2]
References
edit- ^abMochizuki T, Yoshida T, Tanaka R, Forterre P, Sako Y, Prangishvili D (2010)."Diversity of viruses of the hyperthermophilic archaeal genus Aeropyrum, and isolation of the Aeropyrum pernix bacilliform virus 1, APBV1, the first representative of the familyClavaviridae".Virology.402(2): 347–54.doi:10.1016/j.virol.2010.03.046.PMID20430412.
- ^abcdPrangishvili, David; Mochizuki, Tomohiro; Liu, Ying; Krupovic, Mart; ICTV Report Consortium (2019)."ICTV Virus Taxonomy Profile: Clavaviridae".Journal of General Virology.100(9): 1267–1268.doi:10.1099/jgv.0.001295.PMID31271351.
- ^"clava",Wiktionary, the free dictionary,2024-09-24,retrieved2024-10-10
- ^abPtchelkine, D; Gillum, A; Mochizuki, T; Lucas-Staat, S; Liu, Y; Krupovic, M; Phillips, SEV; Prangishvili, D; Huiskonen, JT (10 November 2017)."Unique architecture of thermophilic archaeal virus APBV1 and its genome packaging".Nature Communications.8(1): 1436.Bibcode:2017NatCo...8.1436P.doi:10.1038/s41467-017-01668-0.PMC5681674.PMID29127347.
External links
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