Aring forming reactionorring-closing reactioninorganic chemistryis an umbrella term for a variety of reactions that introduce one or moreringsinto a molecule. Aheterocycle forming reactionis a reaction that introduces a newheterocycle.[1][2] Important classes of ring forming reactions includeannulations[3]andcycloadditions.Heterocyclic compounds are useful in spectroscopic identification of compounds, purity criteria, and investigating the molecular electronic structures.[4]
Named ring forming reactions
editNamed ring forming reactions include (not exhaustive):
- Azide-alkyne Huisgen cycloaddition
- Bischler–Napieralski reaction
- Bucherer carbazole synthesis
- Danheiser annulation
- Dieckmann condensation
- Diels–Alder reaction
- Feist–Benary synthesis
- Fiesselmann thiophene synthesis
- Fischer indole synthesis
- Gewald reaction
- Hantzsch pyridine synthesis
- Larock indole synthesis
- Paal–Knorr synthesis
- Pictet–Spengler reaction
- Pomeranz–Fritsch reaction
- Ring-closing metathesis
- Robinson annulation
- Skraup reaction
References
edit- ^IUPAC,Compendium of Chemical Terminology,2nd ed. (the "Gold Book" ) (1997). Online corrected version: (1995) "Heterocyclic compounds".doi:10.1351/goldbook.H02798
- ^Katritzky, A. R.; Pozharskii, A. F. (2000).Handbook of Heterocyclic Chemistry(2nd ed.). Academic Press.ISBN0080429882.
- ^IUPAC,Compendium of Chemical Terminology,2nd ed. (the "Gold Book" ) (1997). Online corrected version: (2006–) "annulation".doi:10.1351/goldbook.A00367
- ^"Heterocyclic compound - Melting, Boiling, Points | Britannica".www.britannica.com.2024-09-02.Retrieved2024-10-05.
Further reading
edit- Michael B. Smith & Jerry March, 2007, "March's Advanced Organic Chemistry: Reactions, Mechanisms, and Structure," 6th Ed., New York, NY, USA:Wiley & Sons,ISBN0470084944,see[1],accessed 19 June 2015.
- László Kürti & Barbara Czakó, 2005, "Strategic Applications of Named Reactions in Organic Synthesis: Background and Detailed Mechanisms, Amsterdam, NH, NLD:Elsevier Academic Press, 2005ISBN 0124297854, see[2],accessed 19 June 2015.