This articleneeds additional citations forverification.(November 2022) |
Vasopressin analoguesare chemicals similar in function but not necessarily similar in structure tovasopressin(ADH), such asdesmopressin.
Vasopressin analogue | |
---|---|
Drug class | |
Class identifiers | |
Use | Diabetes insipidus,bedwetting,hemophilia A,von Willebrand disease,etc. |
ATC code | H01BA |
Biological target | Vasopressin receptor |
Legal status | |
In Wikidata |
Desmopressin is administered as an oral spray to treat diseases where ADH is either not being produced in sufficient amounts, or vasopressin'sreceptorsare not being stimulated by vasopressin. An example of desmopressin's use is for childhood bed-wetting, where it is believed that children's circadian rhythms are not synchronized with normal light-dark cycles, and consequentially the ADH surge normal children experience at night is not experienced in these children. Taking a desmopressin dose 30–45 minutes before sleeping results in concentrated urine production, and the urination reflex experienced when the bladder fills above a certain level is not triggered.
Used in the treatment of diabetes insipidus.[1]They are also used in cirrhosis patients[2]
References
edit- ^"Desmopressin Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD".www.webmd.com.Retrieved2022-11-10.
- ^Myc, Lukasz A; Stine, Jonathan G; Chakrapani, Rinita; Kadl, Alexandra; Argo, Curtis K (2017-01-18)."Vasopressin use in critically ill cirrhosis patients with catecholamine-resistant septic shock: The CVICU cohort".World Journal of Hepatology.9(2): 106–113.doi:10.4254/wjh.v9.i2.106.ISSN1948-5182.PMC5241528.PMID28144392.