Ventral lateral nucleus

Theventral lateral nucleus(VL) is a nucleus in theventral nuclear groupof thethalamus.

Ventral lateral nucleus
Thalamic nuclei
Identifiers
NeuroNames337
NeuroLexIDbirnlex_1237
Anatomical terms of neuroanatomy

Inputs and outputs

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It receives neuronal inputs from thebasal gangliawhich includes thesubstantia nigraand theglobus pallidus(via thethalamic fasciculus). It also has inputs from thecerebellum(via thedentatothalamic tract).

It sends neuronal output to theprimary motor cortexandpremotor cortex.

The ventral lateral nucleus in the thalamus forms the motor functional division in thethalamic nucleialong with theventral anterior nucleus.The ventral lateral nucleus receives motor information from the cerebellum and the globus pallidus. Output from the ventral lateral nucleus then goes to the primary motor cortex.[1]

Functions

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The function of the ventral lateral nucleus is to target efferents including the motor cortex, premotor cortex, and supplementary motor cortex. Therefore, its function helps the coordination and planning of movement. It also plays a role in the learning of movement.[2]

Clinical significance

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A lesion of the VL has been associated withsynesthesia.[3]

Subdivisions

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The subdivisions of the ventral lateral nucleus include the following nuclei.

  • ventral medial nucleus[4](a.k.a.medial part of ventral lateral nucleus)
  • anterior ventral lateral nucleus[5](pallidalinputs, projects mainly to premotor cortex[6]: 339 )
  • posterior ventral lateral nucleus[7](cerebellar inputs,[6]: 339 principal relay to motor cortex[6]: 337 )

Additional images

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References

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  1. ^Orrison Jr., W. (2008). Atlas of Brain Function. New York: Thieme Medical Publishers, Inc.
  2. ^Crosson, B., (1992). Subcortical Functions in Language and Memory. New York: The Guliford Press.
  3. ^Ro T, Farnè A, Johnson RM, et al. (2007). "Feeling sounds after a thalamic lesion".Annals of Neurology.62(5): 433–41.doi:10.1002/ana.21219.PMID17893864.
  4. ^BrainInfo NeuroName 340
  5. ^BrainInfo NeuroName 338
  6. ^abcJones, E. (1998). "Viewpoint: The core and matrix of thalamic organization".Neuroscience.85(2): 331–345.doi:10.1016/S0306-4522(97)00581-2.PMID9622234.
  7. ^BrainInfo NeuroName 339
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