Central chromatolysisis ahistopathologicchange seen in the cell body of aneuron,where thechromatinandcell nucleusare pushed to the cell periphery, in response toaxonalinjury.[1][2] This response is associated with increased protein synthesis to accommodate for axonal sprouting. In addition to traumatic injuries, central chromatolysis may be caused byvitamin deficiency(pellagra[3]).
See also
editReferences
edit- ^Neuropathology - Basic Reactions. University of Vermont. URL:http:// uvm.edu/~jkessler/NP/neuropbr.htmArchivedJanuary 1, 2010, at theWayback Machine.Accessed on: 1 January 2011.
- ^Holland GR (1996). "Experimental trigeminal nerve injury".Crit. Rev. Oral Biol. Med.7(3): 237–58.PMID8909880.
- ^Piercecchi-Marti MD, Pélissier-Alicot AL, Leonetti G, Tervé JP, Cianfarani F, Pellissier JF (December 2004). "Pellagra: a rare disease observed in a victim of mental and physical abuse".Am J Forensic Med Pathol.25(4): 342–4.doi:10.1097/01.paf.0000136589.28903.e5.PMID15577526.