Polypoid melanomais a rare cutaneous condition, a virulent variant ofnodular melanoma.[1]: 696 Polypoid melanoma is a subtype ofnodular melanoma,the most aggressive form of melanoma (a skin cancer).[2]
| Polypoid melanoma | |
|---|---|
 | |
| Polypoid melanoma of the left ear in 83-year old woman. | |
| Specialty | Dermatology/Oncology |
Signs and symptoms
editPolypoid melanoma is distinguished by a profile that resembles cauliflower and an uneven surface.[3]
Treatment
editTherapies for metastatic melanoma include the biological immunotherapy agentsipilimumab,pembrolizumab,andnivolumab;BRAF inhibitors,such asvemurafenibanddabrafenib;and anMEK inhibitortrametinib.[4]
See also
editReferences
edit- ^James, William D.; Berger, Timothy G.; et al. (2006).Andrews' Diseases of the Skin: clinical Dermatology.Saunders Elsevier.ISBN978-0-7216-2921-6.
- ^Maury, Mikalah E; Jukic, Drazen M (October 13, 2023)."A Case Presentation of Three Polypoid Melanomas With Divergent Features".Cureus.15(10). Springer Science and Business Media LLC: e46951.doi:10.7759/cureus.46951.ISSN2168-8184.PMC10640706.PMID38022238.
- ^Di Altobrando, Ambra; Patrizi, Annalisa; Dika, Emi; Savoia, Francesco (2020)."Cauliflower-like exophytic mass on the skin: polypoid melanoma. Clinical, dermoscopic, and histologic features".Anais Brasileiros de Dermatologia.95(6). Elsevier BV: 748–750.doi:10.1016/j.abd.2020.04.010.ISSN0365-0596.PMC7672400.PMID33041156.
- ^Maverakis E, Cornelius LA, Bowen GM, Phan T, Patel FB, Fitzmaurice S, He Y, Burrall B, Duong C, Kloxin AM, Sultani H, Wilken R, Martinez SR, Patel F (2015)."Metastatic melanoma — a review of current and future treatment options".Acta Derm Venereol.95(5): 516–524.doi:10.2340/00015555-2035.PMID25520039.
Further reading
edit- Hikawa, Renato Shintani; Kanehisa, Eliza Sayuri; Enokihara, Mílvia Maria Simões e Silva; Enokihara, Mauro Yoshiaki; Hirata, Sérgio Henrique (2014)."Polypoid melanoma and superficial spreading melanoma different subtypes in the same lesion".Anais Brasileiros de Dermatologia.89(4). FapUNIFESP (SciELO): 666–668.doi:10.1590/abd1806-4841.20142802.ISSN0365-0596.PMC4148288.PMID25054761.
- Manci, Elizabeth A.; Balch, Charles M.; Murad, Tariq M.; Seng/Jaw, Soong (June 1, 1981). "Polypoid Melanoma, A Virulent Variant of the Nodular Growth Pattern".American Journal of Clinical Pathology.75(6). Oxford University Press (OUP): 810–815.doi:10.1093/ajcp/75.6.810.ISSN0002-9173.PMID7258141.