Acclimatisation (neurons)

Acclimatisationis the process by which the nervous system fails to respond to a stimulus, as a result of the repeated stimulation of a transmission across a synapse. Acclimatisation is believed to occur when thesynaptic knobof the presynapticneuronruns out ofvesiclescontainingneurotransmittersdue to overuse over a short period of time. A synapse that has undergone acclimatisation is said to befatigued.

Acclimatisation is said to be responsible for 'getting used to' background noises and smells.

See also

• Adaptive system
• Neural adaptation