Cloroqualone

Cloroqualone
Clinical data
Pregnancy; category	?;
Routes of; administration	?
ATC code	none;
Pharmacokineticdata
Bioavailability	?
Metabolism	?
Eliminationhalf-life	?
Excretion	?
Identifiers
	IUPAC name 3-(2,6-Dichlorophenyl)-2-ethyl-4-quinazolinone;
CAS Number	25509-07-3;
PubChemCID	63338;
DrugBank	?;
ChemSpider	57005;
UNII	172D4Q6LOW;
ChEMBL	ChEMBL2106114;
CompTox Dashboard(EPA)	DTXSID10180201;
ECHA InfoCard	100.042.761
Chemical and physical data
Formula	C16H12Cl2N2O
Molar mass	319.19g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Clc3cccc(Cl)c3N/1C(=O)c2c(\N=C\1CC)cccc2;
	InChI InChI=1S/C16H12Cl2N2O/c1-2-14-19-13-9-4-3-6-10(13)16(21)20(14)15-11(17)7-5-8-12(15)18/h3-9H,2H2,1H3; Key:SONHVLIDLXLSOL-UHFFFAOYSA-N;
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Cloroqualoneis a quinazolinone-classGABAergicand is an analogue ofmethaqualonedeveloped in the 1980s and marketed mainly in France and some other European countries. It hassedativeandantitussiveproperties resulting from its agonist activity at the β subtype of theGABA_areceptorandsigma-1 receptor,and was sold either alone or in combination with other ingredients as acough medicine.Cloroqualone has weaker sedative properties than methaqualone and was sold for its useful cough-suppressing effects, but was withdrawn from the French market in 1994 because of concerns about its potential for abuse and overdose.^[1]^[2]^[3]

References

^"Cloroqualone".PubChem.U.S. National Library of Medicine.Retrieved2022-07-29.
^Elks J (November 2014).The Dictionary of Drugs: Chemical Data.Springer US. p. 304.ISBN 978-1-4757-2085-3.
^Martindale W, Reynolds JE (1993).Martindale: The Extra Pharmacopoeia(30th ed.). London: The Pharmaceutical Press. p. 745.ISBN 978-0-85369-300-0.

Thissedative-related article is astub.You can help Wikipedia byexpanding it.

[1] "Cloroqualone".PubChem.U.S. National Library of Medicine.Retrieved2022-07-29.

[2] Elks J (November 2014).The Dictionary of Drugs: Chemical Data.Springer US. p. 304.ISBN 978-1-4757-2085-3.

[3] Martindale W, Reynolds JE (1993).Martindale: The Extra Pharmacopoeia(30th ed.). London: The Pharmaceutical Press. p. 745.ISBN 978-0-85369-300-0.

[1]

[2]

[3]

Clinical data

Pregnancy category	?
Routes of administration	?
ATC code	none
Pharmacokineticdata
Bioavailability	?
Metabolism	?
Eliminationhalf-life	?
Excretion	?
Identifiers
IUPAC name 3-(2,6-Dichlorophenyl)-2-ethyl-4-quinazolinone
CAS Number	25509-07-3^N
PubChemCID	63338
DrugBank	?^N
ChemSpider	57005^Y
UNII	172D4Q6LOW
ChEMBL	ChEMBL2106114^N
CompTox Dashboard(EPA)	DTXSID10180201
ECHA InfoCard	100.042.761
Chemical and physical data
Formula	C₁₆H₁₂Cl₂N₂O
Molar mass	319.19g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Clc3cccc(Cl)c3N/1C(=O)c2c(\N=C\1CC)cccc2
InChI InChI=1S/C16H12Cl2N2O/c1-2-14-19-13-9-4-3-6-10(13)16(21)20(14)15-11(17)7-5-8-12(15)18/h3-9H,2H2,1H3^Y Key:SONHVLIDLXLSOL-UHFFFAOYSA-N^Y
^NY(what is this?)(verify)

Cloroqualone

See also

References