This articleis missing informationabout structure (universal).(December 2020) |
Large subunit ribosomal ribonucleic acid(LSU rRNA) is the largest of the two majorRNAcomponents of theribosome. Associated with a number ofribosomal proteins,the LSU rRNA forms the large subunit of the ribosome. The LSU rRNA acts as aribozyme,catalyzingpeptide bond formation.
| LSU rRNA | |
|---|---|
| Identifiers | |
| Symbol | LSU |
| Rfam | CL00112 |
| Other data | |
| PDBstructures | PDBe |
Characteristics
edit| Type | LSU rRNA size | Species | Length | Accession | Reference |
|---|---|---|---|---|---|
| Bacterial (Prokaryotic) | 23S | Escherichia coli | 2,905 nt | NR_076322.1 | [1] |
| Archaeal (Prokaryotic) | 23S | Halobacterium salinarum | 2,906 nt | NR_076247.1 | [2] |
| Eukaryotic | 5.8S&28S | Homo sapiens | 157 + 5,025 nt | NR_145821.1; M11167.1 | [3][4] |
| Mitochondrial | 16S | Homo sapiens | 1,559 nt | NC_012920.1 | [5][6] |
| Plastid | 23S | Arabidopsis thaliana | 2,810 nt | NC_000932.1 | [7] |
Use in phylogenetics
editLSU rRNA sequences are widely used for working outevolutionary relationshipsamong organisms, since they are of ancient origin and are found in all known forms of life.
See also
edit- SSU rRNA:thesmallsubunit ribosomal ribonucleic acid.
References
edit- ^"Escherichia coli23S ribosomal RNA ".3 February 2015.
- ^"Halobacterium salinarum23S ribosomal RNA ".3 February 2015.
- ^"Homo sapiens RNA, 5.8S ribosomal N1 (RNA5-8SN1), ribosomal RNA".3 July 2020.
- ^"Homo sapiens28S ribosomal RNA (nuclear) ".10 November 1986.
- ^Homo sapiensmitochondrion, complete genome."Revised Cambridge Reference Sequence (rCRS): accession NC_012920",National Center for Biotechnology Information.Retrieved on 20 February 2017.
- ^Anderson S, Bankier AT, Barrell BG, de Bruijn MH, Coulson AR, Drouin J, Eperon IC, Nierlich DP, Roe BA, Sanger F, Schreier PH, Smith AJ, Staden R, Young IG (April 1981). "Sequence and organization of the human mitochondrial genome".Nature.290(5806): 457–465.Bibcode:1981Natur.290..457A.doi:10.1038/290457a0.PMID7219534.
- ^"Arabidopsis thaliana23S ribosomal RNA (chloroplast) ".3 April 2023.