Propiverine

Propiverine
Clinical data
AHFS/Drugs	International Drug Names
ATC code	G04BD06(WHO);
Legal status
Legal status	CA:℞-only;
Pharmacokineticdata
Eliminationhalf-life	20.1 h
Identifiers
	IUPAC name 1-methylpiperidin-4-yl diphenyl(propoxy)acetate;
CAS Number	60569-19-9; HCl:54556-98-8;
PubChemCID	4942;
ChemSpider	4773;
UNII	468GE2241L; HCl:DC4GZD10H3;
CompTox Dashboard(EPA)	DTXSID5048265;
Chemical and physical data
Formula	C23H29NO3
Molar mass	367.489g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)OC3CCN(CC3)C;
	InChI InChI=1S/C23H29NO3/c1-3-18-26-23(19-10-6-4-7-11-19,20-12-8-5-9-13-20)22(25)27-21-14-16-24(2)17-15-21/h4-13,21H,3,14-18H2,1-2H3; Key:QPCVHQBVMYCJOM-UHFFFAOYSA-N;
	(what is this?)(verify)

Propiverineis ananticholinergicdrug used for the treatment of urinary urgency, frequency and urge incontinence, all symptoms of overactive bladder syndrome.^[2]^[3]It is amuscarinic antagonist.^[4]

References

^"Digestive and bladder health".Health Canada.9 May 2018.Retrieved13 April2024.
^McKeage K (January 2013). "Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms".Clinical Drug Investigation.33(1): 71–91.doi:10.1007/s40261-012-0046-9.PMID 23288694.S2CID 3399082.
^Huang W, Zong H, Zhou X, Wang T, Zhang Y (December 2015)."Efficacy and Safety of Propiverine Hydrochloride for Overactive Bladder in Adult: a Systematic Review and Meta-analysis".The Indian Journal of Surgery.77(Suppl 3): 1369–1377.doi:10.1007/s12262-015-1264-1.PMC4775592.PMID 27011567.
^BNF 61.London: British Medical Journal Group and Pharmaceutical Press. March 2011. p. 511.ISBN 978-0-85369-962-0.

Thisdrugarticle relating to thegenito-urinary systemis astub.You can help Wikipedia byexpanding it.

[1] "Digestive and bladder health".Health Canada.9 May 2018.Retrieved13 April2024.

[pmid23288694-2] McKeage K (January 2013). "Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms".Clinical Drug Investigation.33(1): 71–91.doi:10.1007/s40261-012-0046-9.PMID 23288694.S2CID 3399082.

[pmid27011567-3] Huang W, Zong H, Zhou X, Wang T, Zhang Y (December 2015)."Efficacy and Safety of Propiverine Hydrochloride for Overactive Bladder in Adult: a Systematic Review and Meta-analysis".The Indian Journal of Surgery.77(Suppl 3): 1369–1377.doi:10.1007/s12262-015-1264-1.PMC4775592.PMID 27011567.

[4] BNF 61.London: British Medical Journal Group and Pharmaceutical Press. March 2011. p. 511.ISBN 978-0-85369-962-0.

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