Stand Up to Cancer(SU2C) is a charitable program of theEntertainment Industry Foundation(EIF). SU2C aims to raise significant funds for translational cancer research through online and televised efforts. Central to the program is a telethon that was first televised by four major broadcast networks (ABC,NBC,CBS,Fox) in over 170 countries on September 5, 2008. SU2C raised over $100 million after that evening's broadcast.[1]Funds collected by Stand Up to Cancer are then distributed by theAmerican Association for Cancer Research.[2]
History
editStand Up to Cancer was conceived of in autumn 2007, by a group of women who had been affected by cancer and believe that by merging the recourse of the media and entertainment industries into a single operation they would be able to fight against this disease in a more profound way.[3]
Stand Up to Cancer was formally launched on May 27, 2008. Current members of the SU2C Council of Founders and Advisors (CFA) includeKatie Couric,Sherry Lansing,Kathleen Lobb, Lisa Paulsen, Rusty Robertson, Sue Schwartz, Pamela Oas Williams, and Ellen Ziffren.[4]All current members of the CFA were co-producers of the 2012 televised special. The late co-founderLaura Ziskinexecutive produced both the September 5, 2008 and September 10, 2010 broadcasts. Sung Poblete, Ph.D., R.N., has served as SU2C’s president and CEO since 2011. In the United Kingdom,Channel 4,along withCancer Research UK,launched its own version ofStand Up to Cancerin October 2012, which has continued every year since.[5]
Initiative
editStand Up to Cancer aims to raise awareness and bring about an understanding that everyone is connected to cancer. The statistic used most often by SU2C is from theAmerican Cancer Society:one out of every two men and one out of every three women will be diagnosed with cancer in their lifetime,[6]meaning everyone is affected in some way, or will be.
The campaign has featured televised moments duringWorld Seriesbaseball games where fans literally "stand up to cancer" by rising and holding signs inscribed with the names of friends and loved ones who have struggled with the disease.[7]
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Fans pay tribute by standing with signs during game 3 of the2015 World Series -
Fans pay tribute by standing with signs at the2016 Major League Baseball All-Star Game -
Fans participate by rising and holding signs at game 4 of the2016 World Series
Research teams funded
editSU2C has donated hundreds of millions of dollars since the first "Dream Team" was organized in 2009. The "Dream Teams" funded by SU2C brings researchers together from institutions and universities across the world and have been among the most productive collaborations in getting new drugs to market and many teams are funded jointly with other cancer research organizations. The research is required to betranslationaland include laboratory and clinical members and cannot involve more than one principal investigator from each institution.[8][9]Many of these dream teams are co-sponsored by other cancer-related foundations.
- SU2C-CRUK-Lustgarten FoundationPancreatic Cancer Dream Team: Reprogramming of Transcriptional Circuitry to Control Pancreatic Cancer ($12 million)
- Stand Up to Cancer (SU2C)-Dutch Cancer SocietyDream Team: Molecular Early Detection of Colorectal Cancer (MEDOCC)
- SU2C-Ovarian Cancer Research Fund Alliance-National Ovarian Cancer CoalitionDream Team: DNA Repair Therapies for Ovarian Cancer
- The SU2C-ACSLung Cancer Dream Team: Targeting KRAS Mutant Lung Cancers
- Tumor Organoids: A New Preclinical Model for Drug Sensitivity Analysis
- Led byHans Clevers,Hans Bos
- The SU2C-TheLustgarten FoundationPancreatic Cancer Convergence Dream Team: Transforming Pancreatic Cancer to Treatable Disease
- SU2C-St. Baldrick’s Pediatric Cancer Dream Team: Immunogenomics to Create New Therapies for High-Risk Childhood Cancers
- SU2C-CRI Dream Team: Immunologic Checkpoint Blockade and Adoptive Cell Transfer in Cancer Therapy
- SU2C-PCF2 Dream Team: Targeting Adaptive Pathways in Metastatic Treatment-Resistant Prostate Cancer
- Led byEric J. Small,Owen Witte
- SU2C-PCF Dream Team: Precision Therapy for Advanced Prostate Cancer
- SU2C-MRA Dream Team: Personalized Medicine for Patients with BRAF Wild-Type Cancer
- An Integrated Approach to Targeting Breast Cancer Molecular Subtypes and their Resistance Phenotype
- Led byJoe W. Gray,Dennis Slamon
- TheVARI-SU2C Epigenetics Dream Team ll
- Bioengineering and Clinical Applications of Circulating Tumor Cell Chip
- Led byDaniel Haber,Mehmet Toner
- Cutting off the Fuel Supply: A New Approach to the Treatment of Pancreatic Cancer ($22 million)
- Targeting PI3K in Women’s Cancers
- SU2C-Lustgarten Foundation Chimeric Antigen Receptor T Cell (CAR-T) Translational Research Team
- SU2C Colorectal Cancer Dream Team: Targeting Genomic, Metabolic and Immunological Vulnerabilities of Colorectal Cancer
Research led by these teams has contributed to the development of two FDA-approved treatments;palbociclib(Breast Cancer Dream Team), andabraxaneplusgemcitabine(Pancreatic Cancer Dream Team).[10]
United States
edit
Six telethons have been broadcast in the United States and are made available to more than 190 countries. To date, more than $603 million[11]has been pledged to support SU2C’s innovative cancer research programs.
The first Stand Up to Cancer event was held on September 5, 2008, raising over $100 million.[1]The second was held on 10 September 2010.[12]The third was held on 7 September 2012, and the fourth was held on 5 September 2014, presented byGwyneth PaltrowandKatie Couricfrom Los Angeles. The fifth was held on 9 September 2016.[13]The averaged combined ratings for the 2014 telethon were 1.8 from 2.1 in 2012.[14]The sixth was broadcast on 7 September 2018, raising more than $123 million. This event was aired on more than 70 broadcast and cable networks and streaming and social platforms, including: CBS, HBO and NBC.[15]
In Canada, the 2014 telethon aired September 5, 2014 insimultaneous substitution(in many areas) with the American telethon, simultaneously on English language networksCBC Television,City,CTVandGlobal,as well asCHCH-DTinHamilton, Ontario,CHEK-DTinVictoria, British Columbia,CJON-DTinSt. John's, Newfoundland and Labrador,and specialty channelsTLN,Fight Network,Gusto TV,AMI-TVand theHollywood Suitechannels. The Canadian broadcast of the telethon benefits EIF Canada, the Canadian arm of the Entertainment Industry Foundation, with all donations benefiting cancer research in Canada.[16]
It was not held in the fall of 2020 due to theCOVID-19 pandemic,but postponed to August 21, 2021.
United Kingdom
editOn 19 October 2012,Channel 4in theUnited Kingdomaired their first telethon for Stand Up to Cancer hosted byDavina McCallandAlan Carralong with Dr.Christian Jessen.A second telethon was broadcast on 17 October 2014, again hosted by McCall and Carr along with Dr. Jessen. Subsequent UK telethons, again on Channel 4, followed in 2016 and 2018.
Stand Up to Cancer's fundraising activities in the UK include the London 3 Peaks Challenge, which involves participants running up the stairs ofHeron Tower,30 St Mary Axeand200 Aldersgatebeforeabseilingdown the outside of200 Aldersgate.[17]
Despite the Original American version cancelling their telethon and ITV giving up on theirText Santashows, Channel 4 have still scheduled a telethon over the last two years, in addition to a number of other charity celebrity specials on the network. The most recent one was held on 15 October 2021,[18]and was hosted by Alan Carr, Adam Hills, Maya Jama and Davina McCall. In addition to this, Channel 4 will be bringing back a version of theBritish Comedy Awardsfor Stand Up to Cancer, with the renamed National Comedy Awards due to be held in London on 15 December 2021.[19]
References
edit- ^abKeveney, Bill (2008-09-08)."Stars 'Stand Up to Cancer,' raise $100M - USATODAY".Usatoday30.usatoday.Retrieved2015-07-26.
- ^Gorman,R.N.,Ali (9 September 2016)."Telethon helping locals stand up to cancer".WPVI-TV.Retrieved10 September2016.
- ^"Stand Up To Cancer — FAQ".Standup2cancer.org. 2008-05-27.Retrieved2015-07-26.
- ^"Stand Up To Cancer — SU2C Leadership".Standup2cancer.org.Retrieved2015-07-26.
- ^"Stand Up To Cancer".Channel 4.Retrieved26 September2012.
- ^ACS Cancer Facts and Figures 2008.Retrieved on 27 May 2008.
- ^"MLB stands up to cancer during Game 4 of Series".Major League Baseball.Retrieved17 October2014.
- ^THE SU2C RESEARCH MODEL
- ^"Stand Up To Cancer Dream Teams".aacr.org.
- ^"Stand Up To Cancer - What We Do".
- ^"With More Than $123.6 Million Pledged So Far in U.S. and Canada in Connection with the Sept. 7 Telecast, Stand Up To Cancer Has Its Best-Ever Fundraising Special - Stand Up to Cancer".Stand Up to Cancer.Retrieved2018-10-30.
- ^"Friday, Sept. 10 TV highlights: 'Stand Up for Cancer' unites networks".Washingtonpost.2010-09-10.Retrieved2015-07-26.
- ^"Stand Up To Cancer — Dine Out with MasterCard and Support a Priceless Cause: Fighting Cancer".Standup2cancer.org. 2015-07-13.Retrieved2015-07-26.
- ^Harp, Justin (2014-09-06)."Friday ratings: Stand Up to Cancer down from 2012 - US TV News".Digital Spy.Retrieved2015-07-26.
- ^"Stand Up To Cancer 2018 Telecast Raises $123.6 Million So Far".Look to the Stars.2018-09-11.Retrieved2019-03-26.
- ^"SU2C Canada - Press Releases".Standup2cancer.ca. 2014-07-09.Retrieved2015-07-26.
- ^"Have you got what it takes to tackle London's Three Peaks Challenge (aka running up three skyscrapers)? – Now. Here. This. – Time Out London".Now-here-this.timeout.Retrieved2015-07-26.
- ^STAND UP TO CANCER RAISES OVER £31 MILLION|Stand Up To Cancer
- ^Home - National Comedy Awards