Andrey RublevdefeatedJiří Veselýin the final, 6–3, 6–4 to win the men's singles title at the 2022 Dubai Tennis Championships. It was Rublev's tenth career singles title. Veselý entered the tournament ranked as the world No. 123, and was the lowest-ranked finalist in the tournament's history.
This tournament markedNovak Djokovic’s first appearance of the season, as he was unable to compete at theAustralian Opendue to the cancellation of his visa. As a result of his quarterfinal loss to Veselý, Djokovic lost theworld No. 1ranking toDaniil Medvedev.[2]