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6-CAT

From Wikipedia, the free encyclopedia
6-CAT
Clinical data
Routes of
administration
Oral
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • 6-Chloro-1,2,3,4-tetrahydronaphtalen-2-amine
CAS Number
PubChemCID
ChemSpider
CompTox Dashboard(EPA)
Chemical and physical data
3D model (JSmol)
  • C1CC2=C(CC1N)C=CC(=C2)Cl
  • InChI=1S/C10H12ClN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1,3,5,10H,2,4,6,12H2checkY
  • Key:CJRJTCMSQLEPFQ-UHFFFAOYSA-NcheckY
(verify)

6-Chloro-2-aminotetralin(6-CAT) is adrugwhich acts as aselective serotonin releasing agent(SSRA) and is a putativeentactogenin humans.[1][2]It is a rigidanalogueofpara-chloroamphetamine(PCA).[1]

According to Nicholset al.,[3]6-CAT is a non-neurotoxic analog ofPCA.

See also

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References

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  1. ^abFuller RW, Perry KW, Baker JC, Molloy BB (November 1974). "6-Chloro-2-aminotetralin, a rigid Conformational analog of 4-chloroamphetamine: pharmacologic properties of it and related compounds in rats".Archives Internationales de Pharmacodynamie et de Therapie.212(1): 141–53.PMID4455127.
  2. ^Fuller RW, Wong DT, Snoddy HD, Bymaster FP (1977). "Comparison of the effects of 6-chloro-2-aminotetralin and of ORG 6582, a related chloroamphetamine analog, on brain serotonin metabolism in rats".Biochemical Pharmacology.26(1): 1, 333–1, 337.doi:10.1016/0006-2952(77)90094-6.
  3. ^Johnson MP, Frescas SP, Oberlender R, Nichols DE (May 1991). "Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3,4-(methylenedioxy)methamphetamine (MDMA)".Journal of Medicinal Chemistry.34(5): 1662–8.doi:10.1021/jm00109a020.PMID1674539.