AGN-2979

AGN-2979
Clinical data
ATC code	None;
Identifiers
	IUPAC name 3-(3-Dimethylaminopropyl)-3-(3-methoxyphenyl)-4,4-dimethyl-piperidine-2,6-dione;
CAS Number	53873-21-5103353-87-3 (HCl);
PubChemCID	40914;
ChemSpider	37360;
UNII	P4HXVYBZ5F;
CompTox Dashboard(EPA)	DTXSID30968644;
Chemical and physical data
Formula	C19H28N2O3
Molar mass	332.444g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C1NC(=O)CC(C1(c2cccc(OC)c2)CCCN(C)C)(C)C;
	InChI InChI=1S/C19H28N2O3/c1-18(2)13-16(22)20-17(23)19(18,10-7-11-21(3)4)14-8-6-9-15(12-14)24-5/h6,8-9,12H,7,10-11,13H2,1-5H3,(H,20,22,23); Key:UJFNSGBGJMRZKS-UHFFFAOYSA-N;
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References[edit]

^Hasegawa S, Kanemaru K, Gittos M, Diksic M (October 2005). "The tryptophan hydroxylase activation inhibitor, AGN-2979, decreases regional 5-HT synthesis in the rat brain measured with alpha-[14C]methyl-L-tryptophan: an autoradiographic study".Brain Research Bulletin.67(3): 248–55.doi:10.1016/j.brainresbull.2005.07.009.PMID 16144662.S2CID 41905586.
^^a ^bGittos MW, Papp M (October 2001). "Antidepressant-like action of AGN 2979, a tryptophan hydroxylase activation inhibitor, in a chronic mild stress model of depression in rats".European Neuropsychopharmacology.11(5): 351–7.doi:10.1016/S0924-977X(01)00103-1.PMID 11597821.S2CID 46635727.

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