AP2A2
Appearance
AP-2 complex subunit alpha-2is aproteinthat in humans is encoded by theAP2A2gene.[5][6][7]
Interactions
[edit]AP2A2 has been shown tointeractwithEPN1[8]andSHC1.[9]
References
[edit]- ^abcENSG00000280759, ENSG00000183020 GRCh38: Ensembl release 89: ENSG00000281385, ENSG00000280759, ENSG00000183020–Ensembl,May 2017
- ^abcGRCm38: Ensembl release 89: ENSMUSG00000002957–Ensembl,May 2017
- ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998)."Huntingtin interacts with a family of WW domain proteins".Human Molecular Genetics.7(9): 1463–74.doi:10.1093/hmg/7.9.1463.PMID9700202.
- ^Robinson MS (Mar 1989)."Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins)".The Journal of Cell Biology.108(3): 833–42.doi:10.1083/jcb.108.3.833.PMC2115374.PMID2564002.
- ^"Entrez Gene: AP2A2 adaptor-related protein complex 2, alpha 2 subunit".
- ^Chen H, Fre S, Slepnev VI, Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P (Aug 1998). "Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis".Nature.394(6695): 793–7.Bibcode:1998Natur.394..793C.doi:10.1038/29555.PMID9723620.S2CID4430975.
- ^Okabayashi Y, Sugimoto Y, Totty NF, Hsuan J, Kido Y, Sakaguchi K, Gout I, Waterfield MD, Kasuga M (Mar 1996)."Interaction of Shc with adaptor protein adaptins".The Journal of Biological Chemistry.271(9): 5265–9.doi:10.1074/jbc.271.9.5265.PMID8617812.
Further reading
[edit]- Kirchhausen T (2000). "Clathrin".Annual Review of Biochemistry.69:699–727.doi:10.1146/annurev.biochem.69.1.699.PMID10966473.
- Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (Jun 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones".DNA Research.9(3): 99–106.CiteSeerX10.1.1.500.923.doi:10.1093/dnares/9.3.99.PMID12168954.
- Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides".Gene.138(1–2): 171–4.doi:10.1016/0378-1119(94)90802-8.PMID8125298.
- David C, McPherson PS, Mundigl O, de Camilli P (Jan 1996)."A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals".Proceedings of the National Academy of Sciences of the United States of America.93(1): 331–5.Bibcode:1996PNAS...93..331D.doi:10.1073/pnas.93.1.331.PMC40232.PMID8552632.
- Okabayashi Y, Sugimoto Y, Totty NF, Hsuan J, Kido Y, Sakaguchi K, Gout I, Waterfield MD, Kasuga M (Mar 1996)."Interaction of Shc with adaptor protein adaptins".The Journal of Biological Chemistry.271(9): 5265–9.doi:10.1074/jbc.271.9.5265.PMID8617812.
- Benmerah A, Bégue B, Dautry-Varsat A, Cerf-Bensussan N (May 1996)."The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein".The Journal of Biological Chemistry.271(20): 12111–6.doi:10.1074/jbc.271.20.12111.PMID8662627.
- van Delft S, Schumacher C, Hage W, Verkleij AJ, van Bergen en Henegouwen PM (Feb 1997)."Association and colocalization of Eps15 with adaptor protein-2 and clathrin".The Journal of Cell Biology.136(4): 811–21.doi:10.1083/jcb.136.4.811.PMC2132490.PMID9049247.
- Ramjaun AR, Micheva KD, Bouchelet I, McPherson PS (Jun 1997)."Identification and characterization of a nerve terminal-enriched amphiphysin isoform".The Journal of Biological Chemistry.272(26): 16700–6.doi:10.1074/jbc.272.26.16700.PMID9195986.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library".Gene.200(1–2): 149–56.doi:10.1016/S0378-1119(97)00411-3.PMID9373149.
- Chen H, Fre S, Slepnev VI, Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P (Aug 1998). "Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis".Nature.394(6695): 793–7.Bibcode:1998Natur.394..793C.doi:10.1038/29555.PMID9723620.S2CID4430975.
- Berlioz-Torrent C, Shacklett BL, Erdtmann L, Delamarre L, Bouchaert I, Sonigo P, Dokhelar MC, Benarous R (Feb 1999)."Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins".Journal of Virology.73(2): 1350–61.doi:10.1128/JVI.73.2.1350-1361.1999.PMC103959.PMID9882340.
- Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998)."Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro".DNA Research.5(6): 355–64.doi:10.1093/dnares/5.6.355.PMID10048485.
- Traub LM, Downs MA, Westrich JL, Fremont DH (Aug 1999)."Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly".Proceedings of the National Academy of Sciences of the United States of America.96(16): 8907–12.Bibcode:1999PNAS...96.8907T.doi:10.1073/pnas.96.16.8907.PMC17706.PMID10430869.
- Page LJ, Sowerby PJ, Lui WW, Robinson MS (Sep 1999)."Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin".The Journal of Cell Biology.146(5): 993–1004.doi:10.1083/jcb.146.5.993.PMC2169493.PMID10477754.
- Kim ST, Lim DS, Canman CE, Kastan MB (Dec 1999)."Substrate specificities and identification of putative substrates of ATM kinase family members".The Journal of Biological Chemistry.274(53): 37538–43.doi:10.1074/jbc.274.53.37538.PMID10608806.
- Slepnev VI, Ochoa GC, Butler MH, De Camilli P (Jun 2000)."Tandem arrangement of the clathrin and AP-2 binding domains in amphiphysin 1 and disruption of clathrin coat function by amphiphysin fragments comprising these sites".The Journal of Biological Chemistry.275(23): 17583–9.doi:10.1074/jbc.M910430199.PMID10748223.
- Jullien-Flores V, Mahé Y, Mirey G, Leprince C, Meunier-Bisceuil B, Sorkin A, Camonis JH (Aug 2000)."RLIP76, an effector of the GTPase Ral, interacts with the AP2 complex: involvement of the Ral pathway in receptor endocytosis"(PDF).Journal of Cell Science.113(16): 2837–44.doi:10.1242/jcs.113.16.2837.PMID10910768.
External links
[edit]- HumanAP2A2genome location andAP2A2gene details page in theUCSC Genome Browser.