ARR3

ARR3
Available structures PDB Ortholog search:PDBeRCSB List of PDB id codes 1XEH,2A34
Identifiers
Aliases	ARR3,ARRX, cArr, arrestin 3 retinal (X-arrestin), arrestin 3, MYP26
External IDs	OMIM:301770;MGI:2159617;HomoloGene:3182;GeneCards:ARR3;OMA:ARR3 - orthologs
Gene location (Human) Chr. X chromosome (human) Band Xq13.1 Start 70,268,305bp End 70,281,840bp
Gene location (Mouse) Chr. X chromosome (mouse) Band X|X C3 Start 99,649,103bp End 99,662,099bp
RNA expressionpattern Bgee Human Mouse(ortholog) Top expressed in testicle retina retinal pigment epithelium sural nerve stromal cell of endometrium rectum mononuclear cell monocyte skin of abdomen skin of leg Top expressed in neural layer of retina epithelium of lens morula retinal pigment epithelium embryo blastocyst primary visual cortex zygote superior frontal gyrus outer nuclear layer More reference expression data BioGPS More reference expression data
Gene ontology Molecular function phosphoprotein binding opsin binding protein binding G protein-coupled receptor binding Cellular component photoreceptor inner segment cytoplasm photoreceptor outer segment synapse Biological process regulation of protein phosphorylation endocytosis signal transduction visual perception response to stimulus G protein-coupled receptor internalization Sources:Amigo/QuickGO
Orthologs Species Human Mouse Entrez 407 170735 Ensembl ENSG00000120500 ENSMUSG00000060890 UniProt P36575 Q9EQP6 RefSeq (mRNA) NM_004312 NM_133205 RefSeq (protein) NP_004303 NP_573468 Location (UCSC) Chr X: 70.27 – 70.28 Mb Chr X: 99.65 – 99.66 Mb PubMedsearch
Wikidata
View/Edit Human View/Edit Mouse

Arrestin-C,also known asretinal cone arrestin-3,is aproteinthat in humans is encoded by theARR3gene.

See also

• Arrestin

Further reading

• Craft CM, Whitmore DH, Wiechmann AF (1994)."Cone arrestin identified by targeting expression of a functional family".J. Biol. Chem.269(6): 4613–9.doi:10.1016/S0021-9258(17)41820-5.PMID8308033.
• Sakuma H, Inana G, Murakami A, et al. (1996)."Immunolocalization of X-arrestin in human cone photoreceptors".FEBS Lett.382(1–2): 105–10.doi:10.1016/0014-5793(96)00163-9.PMID8612728.
• ter Haar E, Musacchio A, Harrison SC, Kirchhausen T (1998)."Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker".Cell.95(4): 563–73.doi:10.1016/S0092-8674(00)81623-2.PMC4428171.PMID9827808.
• Orsini MJ, Benovic JL (1999)."Characterization of dominant negative arrestins that inhibit beta2-adrenergic receptor internalization by distinct mechanisms".J. Biol. Chem.273(51): 34616–22.doi:10.1074/jbc.273.51.34616.PMID9852134.
• Sakuma H, Murakami A, Fujimaki T, Inana G (1999)."Isolation and characterization of the human X-arrestin gene".Gene.224(1–2): 87–95.doi:10.1016/S0378-1119(98)00510-1.PMID9931451.
• John SK, Smith JE, Aguirre GD, Milam AH (2000). "Loss of cone molecular markers in rhodopsin-mutant human retinas with retinitis pigmentosa".Mol. Vis.6:204–15.PMID11063754.
• Chen Z, Dupré DJ, Le Gouill C, et al. (2002)."Agonist-induced internalization of the platelet-activating factor receptor is dependent on arrestins but independent of G-protein activation. Role of the C terminus and the (D/N)PXXY motif".J. Biol. Chem.277(9): 7356–62.doi:10.1074/jbc.M110058200.PMID11729201.
• Kim YM, Barak LS, Caron MG, Benovic JL (2002)."Regulation of arrestin-3 phosphorylation by casein kinase II".J. Biol. Chem.277(19): 16837–46.doi:10.1074/jbc.M201379200.PMID11877451.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003)."Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences".Proc. Natl. Acad. Sci. U.S.A.99(26): 16899–903.Bibcode:2002PNAS...9916899M.doi:10.1073/pnas.242603899.PMC139241.PMID12477932.
• Zhu X, Li A, Brown B, et al. (2002). "Mouse cone arrestin expression pattern: light induced translocation in cone photoreceptors".Mol. Vis.8:462–71.PMID12486395.
• Zhang H, Cuenca N, Ivanova T, et al. (2003)."Identification and light-dependent translocation of a cone-specific antigen, cone arrestin, recognized by monoclonal antibody 7G6".Invest. Ophthalmol. Vis. Sci.44(7): 2858–67.doi:10.1167/iovs.03-0072.hdl:10045/13046.PMID12824223.
• Krishnamurthy H, Galet C, Ascoli M (2004). "The association of arrestin-3 with the follitropin receptor depends on receptor activation and phosphorylation".Mol. Cell. Endocrinol.204(1–2): 127–40.doi:10.1016/S0303-7207(03)00088-1.PMID12850288.S2CID25222855.
• Zhu X, Brown B, Li A, et al. (2003)."GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina".J. Neurosci.23(14): 6152–60.doi:10.1523/JNEUROSCI.23-14-06152.2003.PMC6740345.PMID12853434.
• Ermakova NA, Alekberova ZS, Prokaeva TB (2004). "Autoimmunity to S-Antigen and Retinal Vasculitis in Patients with Behçet's Disease".Adamantiades-Behçet's Disease.Advances in Experimental Medicine and Biology. Vol. 528. pp. 279–81.doi:10.1007/0-306-48382-3_56.ISBN978-0-306-47757-7.PMID12918707.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004)."The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)".Genome Res.14(10B): 2121–7.doi:10.1101/gr.2596504.PMC528928.PMID15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005)."The DNA sequence of the human X chromosome".Nature.434(7031): 325–37.Bibcode:2005Natur.434..325R.doi:10.1038/nature03440.PMC2665286.PMID15772651.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network".Nature.437(7062): 1173–8.Bibcode:2005Natur.437.1173R.doi:10.1038/nature04209.PMID16189514.S2CID4427026.
• Ewing RM, Chu P, Elisma F, et al. (2007)."Large-scale mapping of human protein-protein interactions by mass spectrometry".Mol. Syst. Biol.3(1): 89.doi:10.1038/msb4100134.PMC1847948.PMID17353931.

External links

• HumanARR3genome location andARR3gene details page in theUCSC Genome Browser.