Adrian Hayday

Adrian Hayday
FRS FMedSci
Adrian Hayday FRSFMedSci
	Hayday in 2016
Born	April 1956 (age 68)
Alma mater	University of Cambridge(BA); Imperial College London(PhD);
Awards	FMedSci(2001)[citation needed]; FRS(2016);
	Scientific career
Fields	T cells; Immunosurveillance; Tumourimmunology;
Institutions	King's College London; London Research Institute; Francis Crick Institute; Yale University; MIT;
Thesis	Structure and activity of integrated polyoma viral DNA in transformed rat cells(1979)
Academic advisors	Susumu Tonegawa; Mike Fried[citation needed];
Website	crick.ac.uk/research/a-z-researchers/researchers-d-h/adrian-hayday/; www.kcl.ac.uk/lsm/research/divisions/diiid/departments/immunobiology/research/hayday;

Adrian Clive HaydayFRS FMedSci^[1](born April 1956)^[3]is the Kay Glendinning professor and chair in the Department ofImmunobiologyatKing's College Londonand group leader at theFrancis Crick Institutein the UK.^[4]^[5]

Education

Hayday was educated atQueens' College, Cambridge,where he was awarded a Bachelor of Arts degree innatural sciences (biochemistry)in 1978.^[2]^[1]He went on to complete his PhD inmolecular virologyofPolyomaviridaeatImperial College Londonin 1982.^[6]

Career and research

Hayday began studying immunology as apostdoctoral researcherin 1982 atMassachusetts Institute of Technology (MIT)supervised bySusumu Tonegawa,^[2]^[7]where he identified the molecular basis ofoncogeneactivation inBurkitt's lymphoma.Thereafter, he first described the genes defininggamma-delta T cells,an evolutionarily conserved yet wholly unanticipated set oflymphocytes.AtYale University,King's College London School of Medicineand theFrancis Crick Institute,Hayday established that gamma-delta T cells are distinct from otherT cells,commonly monitoring body-surface integrity rather than specific infections. Their rapid responses to tissue dysregulation offer protection fromcarcinogenesis,underpinning Hayday's and others' ongoing initiatives to employ the cells forimmunotherapy.^[8]

Awards and honours

Hayday has received numerous awards, including the William Clyde DeVane Medal, Yale's highest honour for scholarship and teaching. He was elected to head theBritish Society for Immunology(2005–09), and has formally counselledKing's Health Partners,thePasteur Institute,Kyoto University,theMax Planck Institute,the Allen Institute,MedImmune,theNational Institutes of Health,theWellcome Trust,andCancer Research UKwhose science committee he chairs.^[1]He was elected aFellow of the Royal Society (FRS) in 2016.^[1] He is an honorary member of theBritish Society for Immunology.^[9]

References

^^a ^b ^c ^d ^eAnon (2016)."Professor Adrian Hayday FRS".London:Royal Society.Archived fromthe originalon 29 April 2016.One or more of the preceding sentences incorporates text from the royalsociety.org website where:
"All text published under the heading 'Biography' on Fellow profile pages is available underCreative Commons Attribution 4.0 International License."--"Royal Society Terms, conditions and policies".Archived from the original on 25 September 2015.Retrieved9 March2016.{{cite web}}:CS1 maint: bot: original URL status unknown (link)
^^a ^b ^c ^dAdrian Hayday'sORCID 0000-0002-9495-5793
^Anon (2016)."Adrian Clive HAYDAY".London: companieshouse.gov.uk. Archived fromthe originalon 28 July 2016.
^Anon (2016)."Adrian Hayday: Immunosurveillance Laboratory".London: crick.ac.uk. Archived fromthe originalon 5 April 2015.
^Gibbons, Deena; Fleming, Paul; Virasami, Alex; Michel, Marie-Laure; Sebire, Neil J; Costeloe, Kate; Carr, Robert; Klein, Nigel; Hayday, Adrian (2014). "Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants".Nature Medicine.20(10): 1206–1210.doi:10.1038/nm.3670.PMID 25242415.S2CID 5849557.
^Hayday, Adrian Clive (1982).Structure and activity of integrated polyoma viral DNA in transformed rat cells(PhD thesis). Imperial College London.OCLC 930652868.
^Hayday, A (1985). "Structure, organization, and somatic rearrangement of T cell gamma genes".Cell.40(2): 259–269.doi:10.1016/0092-8674(85)90140-0.PMID 3917858.S2CID 34582929.
^Kiyokawa, Hiroaki; Kineman, Rhonda D; Manova-Todorova, Katia O; Soares, Vera C; Hoffman, Eric S; Ono, Masao; Khanam, Dilruba; Hayday, Adrian C; Frohman, Lawrence A; Koff, Andrew (1996)."Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27Kip1".Cell.85(5): 721–732.doi:10.1016/S0092-8674(00)81238-6.PMID 8646780.
^"Honorary members | British Society for Immunology".

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[frs-1] Anon (2016)."Professor Adrian Hayday FRS".London:Royal Society.Archived fromthe originalon 29 April 2016.One or more of the preceding sentences incorporates text from the royalsociety.org website where:
"All text published under the heading 'Biography' on Fellow profile pages is available underCreative Commons Attribution 4.0 International License."--"Royal Society Terms, conditions and policies".Archived from the original on 25 September 2015.Retrieved9 March2016.{{cite web}}:CS1 maint: bot: original URL status unknown (link)

[orcid-2] Adrian Hayday'sORCID 0000-0002-9495-5793

[companieshouse-3] Anon (2016)."Adrian Clive HAYDAY".London: companieshouse.gov.uk. Archived fromthe originalon 28 July 2016.

[crick-4] Anon (2016)."Adrian Hayday: Immunosurveillance Laboratory".London: crick.ac.uk. Archived fromthe originalon 5 April 2015.

[GibbonsFleming2014-5] Gibbons, Deena; Fleming, Paul; Virasami, Alex; Michel, Marie-Laure; Sebire, Neil J; Costeloe, Kate; Carr, Robert; Klein, Nigel; Hayday, Adrian (2014). "Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants".Nature Medicine.20(10): 1206–1210.doi:10.1038/nm.3670.PMID 25242415.S2CID 5849557.

[phd-6] Hayday, Adrian Clive (1982).Structure and activity of integrated polyoma viral DNA in transformed rat cells(PhD thesis). Imperial College London.OCLC 930652868.

[Hayday1985-7] Hayday, A (1985). "Structure, organization, and somatic rearrangement of T cell gamma genes".Cell.40(2): 259–269.doi:10.1016/0092-8674(85)90140-0.PMID 3917858.S2CID 34582929.

[KiyokawaKineman1996-8] Kiyokawa, Hiroaki; Kineman, Rhonda D; Manova-Todorova, Katia O; Soares, Vera C; Hoffman, Eric S; Ono, Masao; Khanam, Dilruba; Hayday, Adrian C; Frohman, Lawrence A; Koff, Andrew (1996)."Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27Kip1".Cell.85(5): 721–732.doi:10.1016/S0092-8674(00)81238-6.PMID 8646780.

[9] "Honorary members | British Society for Immunology".

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v t e Francis Crick Institute
Funded by	Cancer Research UK Imperial College London King's College London Medical Research Council University College London Wellcome Trust
Senior staff	Simon Boulton Doreen Cantrell David Cooksey Julian Downward Jeremy Farrar Steve Gamblin Peter Gruss Adrian Hayday Caroline S. Hill Tim Hunt Malcolm Irving Harpal Kumar Robin Lovell-Badge Tomas Lindahl Paul Nurse Vassilis Pachnis Anne O'Garra Keith Peters Geraint Rees John Skehel Jim Smith Charles Swanton Richard Treisman Frank Uhlmann Jean-Paul Vincent David Willetts Philip Yea
Incorporating	National Institute for Medical Research London Research Institute

v t e Fellowsof theRoyal Societyelectedin 2016
Fellows	Chris Abell Jas Pal Badyal Steven Balbus Polina Bayvel Graham Bell Martin Bridson John Burrows Katharine Cashman Sarah Cleaveland James Collier Alastair Compston Brian Cox Jack Cuzick Bill David Christl Donnelly Marcus du Sautoy Jim Dunlop Artur Ekert Maria Fitzgerald Antony Galione Pratibha Gai Harry Gilbert Patrick Gill Anne Glover Neil Gow Ian Graham Richard Harvey Adrian Hayday Ramanujan Hegde David Hight Sue Ion Eugenia Kumacheva Corinne Le Quéré Mark Lemmon David Lodge Eleanor Maguire Lakshminarayanan Mahadevan Gil McVean Russell Morris Luke O'Neill Simon Peyton Jones Jonathon Pines Jim Prosser Sriram Ramaswamy Caroline Series Ted Shepherd Alison Smith David Wales Philip Withers Paul Workman
Honorary	Adair Turner
Foreign	Robert Cava Vint Cerf Mark Davis Jennifer Doudna Gerd Faltings John Hayes Svante Pääbo Pasko Rakic Rino Rappuoli Ellen Williams

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