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Alexander Spirin

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Alexander Spirin
Александр Спирин
Born(1931-09-04)4 September 1931
Died30 December 2020(2020-12-30)(aged 89)
EducationDoctor of Science(1962),
Professor,
Academicianof theRussian Academy of Sciences
Alma materMoscow State University (1954)
Scientific career
FieldsBiochemistry,Molecular Biology
InstitutionsMoscow State University
Doctoral advisorAndrey Belozersky

Alexander Sergeevich Spirin(Russian: Александр Сергеевич Спирин; 4 September 1931 – 30 December 2020[1]) was a Russianbiochemist,Distinguished Professor at theLomonosov Moscow State University(since 1999),[2]a Director ofInstitute of Protein Research Russian Academy of Sciences,Puschino(Пущино-на-Оке),Moscow Region(Московская Область), Academician of Russian Academy of Sciences. His primary scientific interests inbiochemistryincludednucleic acidsandproteinbiosynthesis.

Career

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In 1957 together withAndrey Nikolayevich Belozersky(Андрей Николаевич Белозерский) he conducted comparative analysis of bacterialDNAandRNA,[3]and predicted existence of messenger RNA. He gave the first qualitative description of the structure of high-polymer RNA (1959–61). In 1963 he discovered structural transitions ofribosomesand formulated one of the principles of structure of ribosomes. He discovered artificial ribosomal self-assembly (1963–66) and proposed a molecular mechanism of the ribosome role in protein synthesis (1968). He conducted extra-cellular protein synthesis on modified ribosomes — non-enzymatictranslation(together withL.P. Gavrilova) (1970–74).

In 1957, he defended hisCandidate's Dissertation. In 1962, he defended his doctoral dissertation. In 1964, he received the title of Professor. He was elected a corresponding member of the Academy of Sciences of the USSR in 1966 and full member in 1970.

Awards

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Dr. Spirin was awarded theSir Hans Krebs Medalin 1969, elected an Honorary Fellow ofUniversity of Granadain 1972 and awarded the prestigiousDemidov Prizein 2013.[4]In 1974 he was elected a Member of theGerman Academy of Sciences Leopoldina.[5]He was elected an International member of theAmerican Philosophical Societyin 1997[6]and a foreign associate of the USNational Academy of Sciencesin April 2019.[7]

References

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  1. ^Светлая память Спирину Александру Сергеевичу(in Russian)
  2. ^"Заслуженные профессора Московского университета | Летопись Московского университета".
  3. ^Morange, Michel; Cobb, Matthew (2000).A History of Molecular Biology.Harvard University Press. p. 145.ISBN978-0-674-00169-5.Retrieved30 March2011.
  4. ^"Demidov Prize Winners 2013".Russia-infocentre.Retrieved28 November2014.
  5. ^"List of Members".www.leopoldina.org.Archived fromthe originalon 7 October 2017.Retrieved7 October2017.
  6. ^"APS Member History".search.amphilsoc.org.Retrieved2021-12-09.
  7. ^"2019 NAS Election".National Academy of Sciences. April 30, 2019.