Ampiroxicam
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AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral |
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ECHA InfoCard | 100.235.757 |
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Formula | C20H21N3O7S |
Molar mass | 447.46g·mol−1 |
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Chirality | Racemic mixture |
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Ampiroxicam(INN) is anon-steroidal anti-inflammatory drug(NSAID). It is aprodrugofpiroxicam.[1]It has been studied for potentialanticancer activity,but preliminary results did not show evidence of such activity.[2][3]
References[edit]
- ^Carty TJ, Marfat A, Moore PF, Falkner FC, Twomey TM, Weissman A (July 1993). "Ampiroxicam, an anti-inflammatory agent which is a prodrug of piroxicam".Agents and Actions.39(3–4): 157–165.doi:10.1007/BF01998969.PMID8304243.S2CID24284281.
- ^Choi KH, Shim JH, Huong LD, Cho NP, Cho SD (July 2011). "Inhibition of myeloid cell leukemia-1 by tolfenamic acid induces apoptosis in mucoepidermoid carcinoma".Oral Diseases.17(5): 469–475.doi:10.1111/j.1601-0825.2010.01774.x.PMID21496182.
- ^Shim JH, Shin JA, Jung JY, Choi KH, Choi ES, Cho NP, et al. (March 2011). "Chemopreventive effect of tolfenamic acid on KB human cervical cancer cells and tumor xenograft by downregulating specificity protein 1".European Journal of Cancer Prevention.20(2): 102–111.doi:10.1097/CEJ.0b013e328341e38f.PMID21131823.