Bromoderma
| Bromoderma | |
|---|---|
| Other names | Bromoderma tuberosum |
| Specialty | Dermatology |
Bromodermais a skin condition characterized by an eruption ofpapulesandpustuleson the skin.[1]: 135 It is caused by hypersensitivity tobromides,such as those found in certain drugs. There is at least one reported case of bromoderma caused by excessive consumption of asoft drink(Ruby Red Squirt) containingbrominated vegetable oil.[2]
Signs and symptoms
[edit]The disease's symptoms can range from a mildacneiformrash withpapulesandpustulesto more severe conditions likepanniculitis,ulcers, and vegetativenodules,also referred to as tuberous or vegetating bromoderma. Lesions usually affect the lower limbs, scalp, and face.[3][4]
Causes
[edit]One could characterize bromoderma as a kind of delayedhypersensitivity reaction,even though its pathogenesis is still unknown.[5]Lesions can develop as soon as eight days after the medicine is first administered, but they typically do so after a prolonged period of use. High sebaceous gland concentrations on the skin are typically the site of lesions.[6]
Diagnosis
[edit]Skin lesions, a patient's history of usingbromide,and the healing of lesions following drug withdrawal can all be used to make a diagnosis.[7]
See also
[edit]References
[edit]- ^James WD, Berger T, Elston D (2006).Andrews' Diseases of the Skin: Clinical Dermatology(10th ed.). Philadelphia: Saunders Elsevier.ISBN978-0-7216-2921-6.
- ^Jih DM, Khanna V, Somach SC (May 2003)."Bromoderma after excessive ingestion of Ruby Red Squirt".The New England Journal of Medicine.348(19): 1932–1934.doi:10.1056/NEJM200305083481921.PMID12736294.
- ^Nabatame, Shin; Saito, Yoshiaki; Sakuma, Hiroshi; Komaki, Hirofumi; Nakagawa, Eiji; Sugai, Kenji; Sasaki, Masayuki; Uchiyama, Kentaro; Kosaka, Maki (2010). "Bromoderma in a patient with migrating partial seizures in infancy".Epilepsy Research.91(2–3). Elsevier BV: 283–288.doi:10.1016/j.eplepsyres.2010.07.008.ISSN0920-1211.PMID20674275.S2CID3408441.
- ^Anzai, Saburo; Fujiwara, Sakuhei; Inuzuka, Miki (2003). "Bromoderma".International Journal of Dermatology.42(5). Wiley: 370–371.doi:10.1046/j.1365-4362.2003.01734.x.ISSN0011-9059.PMID12755974.S2CID221812784.
- ^Maffeis, Laura; Musolino, Maria Carmela; Cambiaghi, Stefano (2008). "Single-plaque vegetating bromoderma".Journal of the American Academy of Dermatology.58(4). Elsevier BV: 682–684.doi:10.1016/j.jaad.2007.08.011.ISSN0190-9622.PMID18342716.
- ^Hoefel, Isadora da Rosa; Camozzato, Fernanda Oliveira; Hagemann, Laura Netto; Rhoden, Deise Louise Bohn; Kiszewski, Ana Elisa (2016)."Bromoderma in an infant".Anais Brasileiros de Dermatologia.91(5 suppl 1). FapUNIFESP (SciELO): 17–19.doi:10.1590/abd1806-4841.20165013.ISSN0365-0596.PMC5324981.PMID28300882.
- ^Bel, Susana; Bartralot, Ramón; García, Daniel; Aparicio, Gloria; Castells, Antonio (2001). "Vegetant Bromoderma in an Infant".Pediatric Dermatology.18(4). Wiley: 336–338.doi:10.1046/j.1525-1470.2001.01954.x.ISSN0736-8046.PMID11576411.S2CID19631925.
Further reading
[edit]- Paloni, Giulia; Mattei, Ilaria; Ravagnan, Enrico; Cutrone, Mario (2013). "Infantile Bromoderma".The Journal of Pediatrics.163(3). Elsevier BV: 920–920.e1.doi:10.1016/j.jpeds.2013.03.071.ISSN0022-3476.PMID23651770.