CAR-302,196

CAR-302,196
Identifiers
	IUPAC name (1-methylpiperidin-4-yl) 2-cyclopentyl-2-hydroxypent-3-ynoate;
CAS Number	53034-67-6;
PubChemCID	198289;
ChemSpider	171624;
UNII	TNG83KQW4H;
CompTox Dashboard(EPA)	DTXSID30967536;
Chemical and physical data
Formula	C16H25NO3
Molar mass	279.380g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN1CCC(CC1)OC(=O)C(O)(C#CC)C2CCCC2;
	InChI InChI=1S/C16H25NO3/c1-3-10-16(19,13-6-4-5-7-13)15(18)20-14-8-11-17(2)12-9-14/h13-14,19H,4-9,11-12H2,1-2H3; Key:GKCPDYHGDHCIJL-UHFFFAOYSA-N;
	(verify)

CAR-302,196(also known asPCMGor just by its code number302196) is a moderately potent and relatively short lastinganticholinergic deliriantdrug, related to thechemical warfare agent 3-Quinuclidinyl benzilate(QNB). It was developed under contract toEdgewood Arsenalduring the 1960s as part of theUS military chemical weapons program,during research to improve upon the properties of earlier agents such as QNB.

CAR-302,196 was found to be only around 1/4 the potency of QNB, but its onset of action was much faster at only a few minutes, and the duration far shorter at only 2–3 hours. A fast-acting and short-lasting anticholinergic drug was felt to be more desirable for some applications.^[1]^[2]

References

^National Research Council (US) Panel on Anticholinesterase Chemicals; National Research Council (US) Panel on Anticholinergic Chemicals (1982).Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents.Vol. 1. The National Academies Press. pp. 206–207.doi:10.17226/740.ISBN 978-0-309-07759-0.PMID 25032448.
^Ketchum JS (2006).Chemical Warfare Secrets Almost Forgotten. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War.ChemBooks Inc.ISBN 978-1-4243-0080-8.

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[1] National Research Council (US) Panel on Anticholinesterase Chemicals; National Research Council (US) Panel on Anticholinergic Chemicals (1982).Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents.Vol. 1. The National Academies Press. pp. 206–207.doi:10.17226/740.ISBN 978-0-309-07759-0.PMID 25032448.

[2] Ketchum JS (2006).Chemical Warfare Secrets Almost Forgotten. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War.ChemBooks Inc.ISBN 978-1-4243-0080-8.

[1]

[2]

See also

References