CD177
Appearance
CD177 antigenis aproteinthat in humans is encoded by theCD177gene.[5][6][7]
NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971). [supplied by OMIM][7]
See also
[edit]References
[edit]- ^abcGRCh38: Ensembl release 89: ENSG00000204936–Ensembl,May 2017
- ^abcGRCm38: Ensembl release 89: ENSMUSG00000052212–Ensembl,May 2017
- ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^Temerinac S, Klippel S, Strunck E, Roder S, Lubbert M, Lange W, Azemar M, Meinhardt G, Schaefer HE, Pahl HL (May 2000). "Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera".Blood.95(8): 2569–76.doi:10.1182/blood.V95.8.2569.PMID10753836.
- ^Lalezari P, Murphy GB, Allen FH Jr (Jun 1971)."NB1, a new neutrophil-specific antigen involved in the pathogenesis of neonatal neutropenia".J Clin Invest.50(5): 1108–15.doi:10.1172/JCI106582.PMC292033.PMID5552408.
- ^ab"Entrez Gene: CD177 CD177 molecule".
Further reading
[edit]- Stroncek D (2003)."Neutrophil-specific antigen HNA-2a (NB1, CD177): serology, biochemistry, and molecular biology".Vox Sang.83(Suppl 1): 359–61.doi:10.1111/j.1423-0410.2002.tb05334.x.PMID12617169.S2CID36683379.
- Pahl HL (2003). "PRV-1 mRNA expression and other molecular markers in polycythemia rubra vera".Curr. Hematol. Rep.2(3): 231–6.PMID12901344.
- Kralovics R, Skoda RC (2005). "Molecular pathogenesis of Philadelphia chromosome negative myeloproliferative disorders".Blood Rev.19(1): 1–13.doi:10.1016/j.blre.2004.02.002.PMID15572213.
- Goldschmeding R, van Dalen CM, Faber N, et al. (1992). "Further characterization of the NB 1 antigen as a variably expressed 56-62 kD GPI-linked glycoprotein of plasma membranes and specific granules of neutrophils".Br. J. Haematol.81(3): 336–45.doi:10.1111/j.1365-2141.1992.tb08237.x.PMID1382544.S2CID11604830.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides".Gene.138(1–2): 171–4.doi:10.1016/0378-1119(94)90802-8.PMID8125298.
- Stroncek DF, Herr GP, Plachta LB (1994). "Neutrophil-specific antigen NB1 inhibits neutrophil-endothelial cell interactions".J. Lab. Clin. Med.123(2): 247–55.PMID8301201.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library".Gene.200(1–2): 149–56.doi:10.1016/S0378-1119(97)00411-3.PMID9373149.
- Kissel K, Santoso S, Hofmann C, et al. (2001)."Molecular basis of the neutrophil glycoprotein NB1 (CD177) involved in the pathogenesis of immune neutropenias and transfusion reactions".Eur. J. Immunol.31(5): 1301–9.doi:10.1002/1521-4141(200105)31:5<1301::AID-IMMU1301>3.0.CO;2-J.PMID11465086.S2CID33769082.
- Bettinotti MP, Olsen A, Stroncek D (2002). "The use of bioinformatics to identify the genomic structure of the gene that encodes neutrophil antigen NB1, CD177".Clin. Immunol.102(2): 138–44.doi:10.1006/clim.2001.5154.PMID11846455.
- Kissel K, Scheffler S, Kerowgan M, Bux J (2002)."Molecular basis of NB1 (HNA-2a, CD177) deficiency".Blood.99(11): 4231–3.doi:10.1182/blood.V99.11.4231.PMID12010833.
- Klippel S, Strunck E, Busse CE, et al. (2002)."Biochemical characterization of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera".Blood.100(7): 2441–8.doi:10.1182/blood-2002-03-0949.PMID12239154.
- Teofili L, Martini M, Luongo M, et al. (2002). "Overexpression of the polycythemia rubra vera-1 gene in essential thrombocythemia".J. Clin. Oncol.20(20): 4249–54.doi:10.1200/JCO.2002.11.507.PMID12377969.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003)."Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences".Proc. Natl. Acad. Sci. U.S.A.99(26): 16899–903.Bibcode:2002PNAS...9916899M.doi:10.1073/pnas.242603899.PMC139241.PMID12477932.
- Najfeld V, Fuchs S, Merando P, et al. (2003)."Fluorescence in situ hybridization analysis of the PRV-1 gene in polycythemia vera: implications for its role in diagnosis and pathogenesis".Exp. Hematol.31(2): 118–21.doi:10.1016/S0301-472X(02)01032-9.PMID12591276.
- Wolff J, Brendel C, Fink L, et al. (2003)."Lack of NB1 GP (CD177/HNA-2a) gene transcription in NB1 GP- neutrophils from NB1 GP-expressing individuals and association of low expression with NB1 gene polymorphisms".Blood.102(2): 731–3.doi:10.1182/blood-2002-09-2831.PMID12623849.
- Johansson P, Andréasson B, Safai-Kutti S, et al. (2003). "The presence of a significant association between elevated PRV-1 mRNA expression and low plasma erythropoietin concentration in essential thrombocythaemia".Eur. J. Haematol.70(6): 358–62.doi:10.1034/j.1600-0609.2003.00079.x.PMID12756017.S2CID13222207.
External links
[edit]- CD177+Antigenat the U.S. National Library of MedicineMedical Subject Headings(MeSH)
- HumanCD177genome location andCD177gene details page in theUCSC Genome Browser.