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Chlorquinaldol

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Chlorquinaldol
Skeletal formula of chlorquinaldol
Names
Preferred IUPAC name
5,7-Dichloro-2-methylquinolin-8-ol
Other names
Anginazol; Lacoid, Nerisone
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.718Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3checkY
    Key: GPTXWRGISTZRIO-UHFFFAOYSA-NcheckY
  • InChI=1/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3
    Key: GPTXWRGISTZRIO-UHFFFAOYAU
  • Clc1c(O)c2nc(ccc2c(Cl)c1)C
Properties
C10H7Cl2NO
Molar mass 228.07 g/mol
Pharmacology
D08AH02(WHO)G01AC03(WHO),P01AA04(WHO),R02AA11(WHO)
Except where otherwise noted, data are given for materials in theirstandard state(at 25 °C [77 °F], 100 kPa).

Chlorquinaldolis anantimicrobialagent and antiseptic.[1]It is achlorinatedderivative of the popular chelating agent8-hydroxyquinoline.It is applied topically as a cream and internally as alosenge.[2]

It was marketed byGeigyas an intestinal antiseptic andamebicidewith the trade nameSiosteran.[citation needed]

References

[edit]
  1. ^Mett H, Gyr K, Zak O, Vosbeck K (July 1984)."Duodeno-pancreatic secretions enhance bactericidal activity of antimicrobial drugs".Antimicrob. Agents Chemother.26(1): 35–8.doi:10.1128/aac.26.1.35.PMC179912.PMID6236746.
  2. ^Kutscher, Bernhard (2020). "Dermatologicals ( D ), 4. Antiseptics and Disinfectants ( D 08), Anti‐Acne Preparations ( D 10), and Other Dermatological Preparations ( D 11)".Ullmann's Encyclopedia of Industrial Chemistry.Weinheim: Wiley-VCH. pp. 1–22.doi:10.1002/14356007.w08_w03.ISBN978-3527306732.