Corrinoid

Corrin ring, numbered according to the 1975 IUPAC standard. Note that for consistency with theporphyrinnumbering system, there is no 20 position. Positions 21-24 were numbered 20-23 in earlier literature.^[1]

Corrinoidsare a group of compounds based on the skeleton ofcorrin,a cyclic system containing fourpyrrolerings similar toporphyrins.^[2]These include compounds based on octadehydrocorrin, which has the trivial namecorrole.^[3]

Thecobalamins(vitamin B₁₂) are the best known members of the group. Other prominent examples includecobyrinic acidand its hexaamidecobyric acid;cobinic acidand its hexaamidecobinamide;cobamic acidandcobamide.

Compounds containing the "Cob-" prefix (notcorrin) are cobalt derivatives, and may include anoxidation state,as in "Cob(II)alamin". When cobalt is replaced by another metal or hydrogen, the name changes accordingly, as inferrobamic acidorhydrogenobamic acid.

Reactions with cyanide

A solution of aquacyano-corrinoids, such ascobalaminorcobinamide,reacts with free cyanide in an aqueous sample. The binding of cyanide to the corrinoid cobalt center leads to a color change from orange to violet.^[4]Quantification of the cyanide content is feasible byUV-vis spectroscopy.^[5]^[6]Absorption of the corrinoid on a solid phase,^[7]allows detection of cyanide even in colored samples, rendering this method appropriate for the analysis of cyanide in water, wastewater, blood, and food.^[8]^[9]Furthermore, this technology is non-toxic and considerably less prone to interference than the pyridine-barbituric acid colorimetry method.

References

^Dorothy Crowfoot Hodgkin (1965-11-16). "The Structure of the Corrin Nucleus from X-ray Analysis".Proceedings of the Royal Society of London. Series A, Mathematical and Physical Sciences.288(1414): 294–305.Bibcode:1965RSPSA.288..294H.doi:10.1098/rspa.1965.0219.JSTOR 2415001.S2CID 95235740.
^Cracan, Valentin; Banerjee, Ruma (2013). "Chapter 10 Cobalt and Corrinoid Transport and Biochemistry". In Banci, Lucia (ed.).Metallomics and the Cell.Metal Ions in Life Sciences. Vol. 12. Springer. pp. 333–374.doi:10.1007/978-94-007-5561-1_10.ISBN 978-94-007-5560-4.PMID 23595677.electronic-bookISBN 978-94-007-5561-1ISSN 1559-0836electronic-ISSN 1868-0402
^"The Nomenclature of Corrinoids: Recommendations 1975".IUPAC-IUB Commission on Biochemical Nomenclature (CBN). 1975. Archived fromthe originalon 2012-10-28.Retrieved2006-06-19.
^Pratt, J.M. (1972).Inorganic Chemistry of Vitamin B12.Academic Press. p. 44.
^Zelder, F.H. (2008). "Specific Colorimetric Detection of Cyanide Triggered by a Conformational Switch in Vitamin B12".Inorganic Chemistry.47(4): 1264–1266.doi:10.1021/ic702368b.PMID 18205304.
^Mannel-Croise, Zelder (2009). "Side chains of cobalt corrinoids control the sensitivity and selectivity in the colorimetric detection of cyanide".Inorganic Chemistry.48(4): 1272–1274.doi:10.1021/ic900053h.PMID 19161297.
^Mannel-Croise, Zelder (2012). "Complex samples cyanide detection with immobilized corrinoids".ACS Applied Materials & Interfaces.4(2): 725–729.doi:10.1021/am201357u.PMID 22211318.
^Tivana, Da Cruz Francisco, Zelder, Bergenståhl, Dejmek (2014)."Straightforward rapid spectrophotometric quantification of total cyanogenic glycosides in fresh and processed cassava products"(PDF).Food Chemistry.158:20–27.doi:10.1016/j.foodchem.2014.02.066.PMID 24731309.{{cite journal}}:CS1 maint: multiple names: authors list (link)
^Mannel-Croise, Zelder (2012)."Rapid visual detection of blood cyanide"(PDF).Analytical Methods.4(9): 2632–2634.doi:10.1039/c2ay25595b.S2CID 96719554.

External links

Corrinoidsat the U.S. National Library of MedicineMedical Subject Headings(MeSH)
"The Nomenclature of Corrinoids" at chem.qmul.ac.uk
Goldbook

This article about aheterocyclic compoundis astub.You can help Wikipedia byexpanding it.

[1] Dorothy Crowfoot Hodgkin (1965-11-16). "The Structure of the Corrin Nucleus from X-ray Analysis".Proceedings of the Royal Society of London. Series A, Mathematical and Physical Sciences.288(1414): 294–305.Bibcode:1965RSPSA.288..294H.doi:10.1098/rspa.1965.0219.JSTOR 2415001.S2CID 95235740.

[2] Cracan, Valentin; Banerjee, Ruma (2013). "Chapter 10 Cobalt and Corrinoid Transport and Biochemistry". In Banci, Lucia (ed.).Metallomics and the Cell.Metal Ions in Life Sciences. Vol. 12. Springer. pp. 333–374.doi:10.1007/978-94-007-5561-1_10.ISBN 978-94-007-5560-4.PMID 23595677.electronic-bookISBN 978-94-007-5561-1ISSN 1559-0836electronic-ISSN 1868-0402

[3] "The Nomenclature of Corrinoids: Recommendations 1975".IUPAC-IUB Commission on Biochemical Nomenclature (CBN). 1975. Archived fromthe originalon 2012-10-28.Retrieved2006-06-19.

[4] Pratt, J.M. (1972).Inorganic Chemistry of Vitamin B12.Academic Press. p. 44.

[5] Zelder, F.H. (2008). "Specific Colorimetric Detection of Cyanide Triggered by a Conformational Switch in Vitamin B12".Inorganic Chemistry.47(4): 1264–1266.doi:10.1021/ic702368b.PMID 18205304.

[6] Mannel-Croise, Zelder (2009). "Side chains of cobalt corrinoids control the sensitivity and selectivity in the colorimetric detection of cyanide".Inorganic Chemistry.48(4): 1272–1274.doi:10.1021/ic900053h.PMID 19161297.

[7] Mannel-Croise, Zelder (2012). "Complex samples cyanide detection with immobilized corrinoids".ACS Applied Materials & Interfaces.4(2): 725–729.doi:10.1021/am201357u.PMID 22211318.

[8] Tivana, Da Cruz Francisco, Zelder, Bergenståhl, Dejmek (2014)."Straightforward rapid spectrophotometric quantification of total cyanogenic glycosides in fresh and processed cassava products"(PDF).Food Chemistry.158:20–27.doi:10.1016/j.foodchem.2014.02.066.PMID 24731309.{{cite journal}}:CS1 maint: multiple names: authors list (link)

[9] Mannel-Croise, Zelder (2012)."Rapid visual detection of blood cyanide"(PDF).Analytical Methods.4(9): 2632–2634.doi:10.1039/c2ay25595b.S2CID 96719554.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]