Diaminopyrimidine
Diaminopyrimidines(DAP) are a class oforganic chemicalcompounds that include twoaminegroups on apyrimidinering.
They include manydihydrofolate reductase inhibitordrugs(such aspyrimethamine,trimetrexate,andpiritrexim[1]and theantibioticsIclaprimandtrimethoprim).
Some have been patented as anti-cancer drugs.[2]
See also
[edit]References
[edit]- ^http://aac.asm.org/cgi/content/full/45/12/3293Archived2008-08-29 at theWayback Machine"Dicyclic and Tricyclic Diaminopyrimidine Derivatives as Potent Inhibitors of Cryptosporidium parvum Dihydrofolate Reductase: Structure-Activity and Structure-Selectivity Correlations" Nelson et al. 2001
- ^"Archived copy".Archived fromthe originalon 2011-06-05.Retrieved2009-01-05.
{{cite web}}:CS1 maint: archived copy as title (link)
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