EMP1

EMP1
Identifiers
Aliases	EMP1,CL-20, EMP-1, TMP, epithelial membrane protein 1
External IDs	OMIM:602333;MGI:107941;HomoloGene:1088;GeneCards:EMP1;OMA:EMP1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	13,219,941bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	135,360,171bp
RNA expressionpattern
	Top expressed in
	mucosa of pharynx; ; oral cavity; ; amniotic fluid; ; synovial joint; ; body of tongue; ; gums; ; gingival epithelium; ; buccal mucosa cell; ; skin of hip; ; stromal cell of endometrium;
	Top expressed in
	corneal stroma; ; conjunctival fornix; ; belly cord; ; skin of external ear; ; ankle joint; ; left lung lobe; ; skin of back; ; stroma of bone marrow; ; dermis; ; sciatic nerve;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	plasma membrane; membrane; integral component of membrane;
Biological process	multicellular organism development; bleb assembly; cell population proliferation; cell death; epidermis development;
	Sources:Amigo/QuickGO
Orthologs
	2012
	13730
	ENSG00000134531
	ENSMUSG00000030208
	P54849
	P47801
	NM_001423
	NM_001288627; NM_001288628; NM_010128
	NP_001414
	NP_001275556; NP_001275557; NP_034258
	Wikidata
View/Edit Human	View/Edit Mouse

Epithelial membrane protein 1is aproteinthat in humans is encoded by theEMP1gene.^[5]^[6]^[7]

References

^^a ^b ^cGRCh38: Ensembl release 89: ENSG00000134531–Ensembl,May 2017
^^a ^b ^cGRCm38: Ensembl release 89: ENSMUSG00000030208–Ensembl,May 2017
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^Ben-Porath I, Benvenisty N (Feb 1997). "Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins".Gene.183(1–2): 69–75.doi:10.1016/S0378-1119(96)00475-1.PMID 8996089.
^Chen Y, Medvedev A, Ruzanov P, Marvin KW, Jetten AM (May 1997)."cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family".Genomics.41(1): 40–8.doi:10.1006/geno.1997.4524.PMID 9126480.
^"Entrez Gene: EMP1 epithelial membrane protein 1".

Jain A, Tindell CA, Laux I, et al. (2005)."Epithelial membrane protein-1 is a biomarker of gefitinib resistance".Proc. Natl. Acad. Sci. U.S.A.102(33): 11858–63.Bibcode:2005PNAS..10211858J.doi:10.1073/pnas.0502113102.PMC1187965.PMID 16087880.
Gerhard DS, Wagner L, Feingold EA, et al. (2004)."The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)".Genome Res.14(10B): 2121–7.doi:10.1101/gr.2596504.PMC528928.PMID 15489334.
Wang HT, Kong JP, Ding F, et al. (2003)."Analysis of gene expression profile induced by EMP-1 in esophageal cancer cells using cDNA Microarray".World J. Gastroenterol.9(3): 392–8.doi:10.3748/wjg.v9.i3.392.PMC4621547.PMID 12632483.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003)."Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences".Proc. Natl. Acad. Sci. U.S.A.99(26): 16899–903.Bibcode:2002PNAS...9916899M.doi:10.1073/pnas.242603899.PMC139241.PMID 12477932.
Wang HT, Liu ZH, Wang XQ, Wu M (2003). "[Effect of EMP-1 gene on human esophageal cancer cell line]".AI Zheng.21(3): 229–32.PMID 12451984.
Liehr T, Kuhlenbäumer G, Wulf P, et al. (1999). "Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3".Genomics.58(1): 106–8.doi:10.1006/geno.1999.5803.PMID 10331954.
Schiemann S, Rückels M, Engelholm LH, et al. (1997). "Differential gene expression in human mammary carcinoma cells: identification of a new member of a receptor family".Anticancer Res.17(1A): 13–20.PMID 9066625.
Lobsiger CS, Magyar JP, Taylor V, et al. (1997). "Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1".Genomics.36(3): 379–87.doi:10.1006/geno.1996.0482.PMID 8884260.
Ruegg CL, Wu HY, Fagnoni FF, et al. (1996). "B4B, a novel growth-arrest gene, is expressed by a subset of progenitor/pre-B lymphocytes negative for cytoplasmic mu-chain".J. Immunol.157(1): 72–80.doi:10.4049/jimmunol.157.1.72.PMID 8683158.S2CID 13361245.
Marvin KW, Fujimoto W, Jetten AM (1996)."Identification and characterization of a novel squamous cell-associated gene related to PMP22".J. Biol. Chem.270(48): 28910–6.doi:10.1074/jbc.270.48.28910.PMID 7499420.

This article on ageneon humanchromosome 12is astub.You can help Wikipedia byexpanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000134531–Ensembl,May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030208–Ensembl,May 2017

[3] "Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8996089-5] Ben-Porath I, Benvenisty N (Feb 1997). "Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins".Gene.183(1–2): 69–75.doi:10.1016/S0378-1119(96)00475-1.PMID 8996089.

[pmid9126480-6] Chen Y, Medvedev A, Ruzanov P, Marvin KW, Jetten AM (May 1997)."cDNA cloning, genomic structure, and chromosome mapping of the human epithelial membrane protein CL-20 gene (EMP1), a member of the PMP22 family".Genomics.41(1): 40–8.doi:10.1006/geno.1997.4524.PMID 9126480.

[entrez-7] "Entrez Gene: EMP1 epithelial membrane protein 1".

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References

Further reading