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End-diastolic volume

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Incardiovascular physiology,end-diastolic volume(EDV) is the volume of blood in the right or left ventricle at end of filling indiastolewhich is amount of blood present in ventricle at the end of diastole.[1]Because greater EDVs cause greater distention of the ventricle,EDVis often used synonymously withpreload,which refers to the length of thesarcomeresincardiac muscleprior to contraction (systole). An increase in EDV increases the preload on the heart and, through theFrank-Starling mechanismof the heart, increases the amount of blood ejected from the ventricle during systole (stroke volume).[citation needed]

Sample values

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Ventricular volumes
Measure Right ventricle Left ventricle
End-diastolic volume 144 mL (± 23 mL)[2] 142 mL (± 21 mL)[3]
End-diastolic volume / body surface area (mL/m2) 78 mL/m2(± 11 mL/m2)[2] 78 mL/m2(± 8.8 mL/m2)[3]
End-systolic volume 50 mL (± 14 mL)[2] 47 mL (± 10 mL)[3]
End-systolic volume / body surface area (mL/m2) 27 mL/m2(± 7 mL/m2)[2] 26 mL/m2(± 5.1 mL/m2)[3]
Stroke volume 94 mL (± 15 mL)[2] 95 mL (± 14 mL)[3]
Stroke volume / body surface area (mL/m2) 51 mL/m2(± 7 mL/m2)[2] 52 mL/m2(± 6.2 mL/m2)[3]
Ejection fraction 66% (± 6%)[2] 67% (± 4.6%)[3]
Heart rate 60–100bpm[4] 60–100bpm[4]
Cardiac output 4.0–8.0L/minute[5] 4.0–8.0L/minute[5]

The right ventricular end-diastolic volume (RVEDV) ranges between 100 and 160 mL.[5]The right ventricular end-diastolic volume index (RVEDVI) is calculated by RVEDV/BSAand ranges between 60 and 100 mL/m2.[5]

See also

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References

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  1. ^Feger, Joachim."End-diastolic volume | Radiology Reference Article | Radiopaedia.org".Radiopaedia.Retrieved8 August2022.
  2. ^abcdefgMaceira AM, Prasad SK, Khan M, Pennell DJ (December 2006)."Reference right ventricular systolic and diastolic function normalized to age, gender and body surface area from steady-state free precession cardiovascular magnetic resonance"(PDF).European Heart Journal.27(23): 2879–88.doi:10.1093/eurheartj/ehl336.PMID17088316.
  3. ^abcdefgMaceira A (2006). "Normalized Left Ventricular Systolic and Diastolic Function by Steady State Free Precession Cardiovascular Magnetic Resonance".Journal of Cardiovascular Magnetic Resonance.8:417–426.doi:10.1080/10976640600572889.(subscription required)
  4. ^abNormal ranges for heart rate are among the narrowest limits betweenbradycardiaandtachycardia.See theBradycardiaandTachycardiaarticles for more detailed limits.
  5. ^abcd"Normal Hemodynamic Parameters – Adult"(PDF).Edwards Lifesciences LLC. 2009.