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Enprofylline

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Enprofylline
Skeletal formula
Space-filling model of enprofylline
Clinical data
ATC code
  • None
Identifiers
  • 3-Propyl-7H-purine-2,6-dione
CAS Number
PubChemCID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard(EPA)
ECHA InfoCard100.050.166Edit this at Wikidata
Chemical and physical data
FormulaC8H10N4O2
Molar mass194.194g·mol−1
3D model (JSmol)
  • CCCn2c(=O)[nH]c(=O)c1nc[nH]c12
  • InChI=1S/C8H10N4O2/c1-2-3-12-6-5(9-4-10-6)7(13)11-8(12)14/h4H,2-3H2,1H3,(H,9,10)(H,11,13,14)checkY
  • Key:SIQPXVQCUCHWDI-UHFFFAOYSA-NcheckY
☒NcheckY(what is this?)(verify)

Enprofylline(3-propylxanthine) is axanthinederivative used in the treatment ofasthma,which acts as abronchodilator.It acts primarily as a competitive nonselectivephosphodiesterase inhibitorwith relatively little activity as a nonselectiveadenosine receptorantagonist.[1][2]

References[edit]

  1. ^Lunell E, Svedmyr N, Andersson KE, Persson CG (1982). "Effects of enprofylline, a xanthine lacking adenosine receptor antagonism, in patients with chronic obstructive lung disease".European Journal of Clinical Pharmacology.22(5): 395–402.doi:10.1007/bf00542541.PMID6288396.S2CID3240010.
  2. ^Laursen LC (December 1987). "Anti asthmatic effects and pharmacokinetics of enprofylline--a new xanthine derivate".Danish Medical Bulletin.34(6): 289–97.PMID3325233.