Eticlopride

Eticlopride
Clinical data
ATC code	none;
Identifiers
	IUPAC name 5-chloro-3-ethyl-N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-6-methoxybenzamide;
CAS Number	84226-12-0; HCl:97612-24-3;
PubChemCID	57267;
IUPHAR/BPS	966;
ChemSpider	51626;
UNII	J8M468HBH4; HCl:HJ2CAH4TZ1;
ChEMBL	ChEMBL8946;
CompTox Dashboard(EPA)	DTXSID9048435;
Chemical and physical data
Formula	C17H25ClN2O3
Molar mass	340.85g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC1=CC(=C(C(=C1O)C(=O)NCC2CCCN2CC)OC)Cl;
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Eticloprideis a selectivedopamine antagonistthat acts onD₂dopamine receptor.It is primarily used in pharmacological research.^[1]^[2]^[3]^[4]

References

^"Eticlopride hydrochloride".Abcam.
^Claytor R, Lile JA, Nader MA (March 2006). "The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys".Pharmacology, Biochemistry, and Behavior.83(3): 456–64.doi:10.1016/j.pbb.2006.03.007.PMID 16631246.S2CID 39482275.
^Hemby SE, Smith JE, Dworkin SI (June 1996). "The effects of eticlopride and naltrexone on responding maintained by food, cocaine, heroin and cocaine/heroin combinations in rats".The Journal of Pharmacology and Experimental Therapeutics.277(3): 1247–58.PMID 8667185.
^Haile CN, Kosten TA (November 2001). "Differential effects of D1- and D2-like compounds on cocaine self-administration in Lewis and Fischer 344 inbred rats".The Journal of Pharmacology and Experimental Therapeutics.299(2): 509–18.PMID 11602661.

Eticloprideat the U.S. National Library of MedicineMedical Subject Headings(MeSH)

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