Flavone

Flavone
Names
	IUPAC name 2-phenylchromen-4-one
Identifiers
CAS Number	525-82-6;
3D model (JSmol)	Interactive image;
Beilstein Reference	157598
ChEBI	CHEBI:42491;
ChEMBL	ChEMBL275638;
ChemSpider	10230;
DrugBank	DB07776;
ECHA InfoCard	100.007.623
EC Number	208-383-8;
Gmelin Reference	1224858
IUPHAR/BPS	409;
KEGG	C15608;
PubChemCID	10680;
RTECS number	DJ3100630;
UNII	S2V45N7G3B;
CompTox Dashboard(EPA)	DTXSID2022048;
	InChI InChI=1S/C15H10O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-10H Key: VHBFFQKBGNRLFZ-UHFFFAOYSA-N;
	SMILES C1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2;
Properties
Chemical formula	C15H10O2
Molar mass	222.243g·mol−1
Appearance	white solid
Melting point	96–97 °C (205–207 °F; 369–370 K)
	Except where otherwise noted, data are given for materials in theirstandard state(at 25 °C [77 °F], 100 kPa). Infobox references

Flavoneis anorganic compoundwith the formulaC₆H₄OC₃H(Ph)O.A white solid, flavone is a derivative ofchromonewith aphenyl(Ph) substituent adjacent to the ether group. The compound is of little direct practical importance, but susbstituted derivatives, theflavonesandflavonoidsare a large class of nutritionally importantnatural products.^[1]Flavone can be prepared in the laboratory by cyclization of 2-hydroxacetophenone.^[2]Isomeric with flavone isisoflavone,where the phenyl group is adjacent to theketone.

References[edit]

^Gaspar, Alexandra; Matos, Maria João; Garrido, Jorge; Uriarte, Eugenio; Borges, Fernanda (2014)."Chromone: A Valid Scaffold in Medicinal Chemistry".Chemical Reviews.114(9): 4960–4992.doi:10.1021/cr400265z.
^T. S. Wheeler (1952). "Flavone".Organic Syntheses.32:72.doi:10.15227/orgsyn.032.0072.

[1] Gaspar, Alexandra; Matos, Maria João; Garrido, Jorge; Uriarte, Eugenio; Borges, Fernanda (2014)."Chromone: A Valid Scaffold in Medicinal Chemistry".Chemical Reviews.114(9): 4960–4992.doi:10.1021/cr400265z.

[2] T. S. Wheeler (1952). "Flavone".Organic Syntheses.32:72.doi:10.15227/orgsyn.032.0072.

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