Flopristin

Flopristin
Names
	IUPAC name (7R,10R,11R,12Z,17Z,19Z,21S,23R)-23-fluoro-21-hydroxy-11,19-dimethyl-10-propan-2-yl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14-trione
	Other names (16R)-16-Desoxy-16-fluoropristinamycin IIB; RPR 132552; RPR 132552A
Identifiers
CAS Number	318498-76-9;
3D model (JSmol)	Interactive image;
ChemSpider	8090642;
ECHA InfoCard	100.218.104
EC Number	690-752-1;
PubChemCID	21944122;
UNII	OZV2QPB39M;
CompTox Dashboard(EPA)	DTXSID40953763;
	InChI InChI=1S/C28H38FN3O6/c1-17(2)26-19(4)9-10-24(34)30-11-5-7-18(3)13-21(33)14-20(29)15-25-31-22(16-37-25)27(35)32-12-6-8-23(32)28(36)38-26/h5,7,9-10,13,16-17,19-21,23,26,33H,6,8,11-12,14-15H2,1-4H3,(H,30,34)/b7-5-,10-9-,18-13-/t19-,20-,21-,23-,26-/m1/s1 Key: DFSJQGCLWZVMOD-ZITBLJMASA-N;
	SMILES O[C@H](/C=C(C)/C=C/CNC(/C=C/[C@@H](C)[C@H](OC1=O)C(C)C)=O)C[C@@H](F)CC2=NC(C(N3[C@@H]1CCC3)=O)=CO2;
Properties
Chemical formula	C28H38FN3O6
Molar mass	531.625g·mol−1
Hazards
	GHSlabelling:
Pictograms
Signal word	Warning
Hazard statements	H302,H312,H317,H332,H341
Precautionary statements	P201,P202,P261,P264,P270,P271,P272,P280,P281,P301+P312,P302+P352,P304+P312,P304+P340,P308+P313,P312,P321,P322,P330,P333+P313,P363,P405,P501
	Except where otherwise noted, data are given for materials in theirstandard state(at 25 °C [77 °F], 100 kPa). Infobox references

Flopristin is one of the components of the experimental drugNXL103.^[1]

References[edit]

^Pankuch, Glenn A.; Kelly, Linda M.; Lin, Gengrong; Bryskier, Andre; Couturier, Catherine; Jacobs, Michael R.; Appelbaum, Peter C. (2003)."Activities of a new oral streptogramin, XRP 2868, compared to those of other agents against Streptococcus pneumoniae and Haemophilus species".Antimicrobial Agents and Chemotherapy.47(10): 3270–3274.doi:10.1128/AAC.47.10.3270-3274.2003.PMC201162.PMID 14506040.

This systemicantibiotic-related article is astub.You can help Wikipedia byexpanding it.