Flunitrazolam
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| Formula | C17H12FN5O2 |
| Molar mass | 337.314g·mol−1 |
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Flunitrazolam(FNTZ,Flunazolam) is atriazolobenzodiazepine(TBZD), which arebenzodiazepine(BZD) derivatives, that has been sold online as adesigner drug,and is a potenthypnoticandsedativedrug similar to related compounds such asflunitrazepam,clonazolamandflubromazolam.It was first definitively identified and reported to theEMCDDAEarly Warning System, by an analytical laboratory in Germany in October 2016,[2]and had not been described in the scientific or patent literature before this.[3]It is the triazole analogue ofFlunitrazepam(Rohypnol). The addition of thetriazolering to the scaffold increases potency significantly, this is evident as flunitrazolam is reported anecdotally to be active in themicrogramlevel. It is active at 0.1 mg.[4][5]
See also
[edit]References
[edit]- ^Anvisa(2024-05-28)."RDC Nº 877 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial"[Collegiate Board Resolution No. 877 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese).Diário Oficial da União.Archivedfrom the original on 2024-09-25.Retrieved2024-09-25.
- ^"Europol 2016 Annual Report on the implementation of Council Decision 2005/387/JHA"(PDF).
- ^Cornett EM, Novitch MB, Brunk AJ, Davidson KS, Menard BL, Urman RD, Kaye AD (June 2018). "New benzodiazepines for sedation".Best Practice & Research. Clinical Anaesthesiology.32(2): 149–164.doi:10.1016/j.bpa.2018.06.007.PMID30322456.S2CID53501694.
- ^Ameline A, Richeval C, Gaulier JM, Raul JS, Kintz P (July 2018)."Characterization of Flunitrazolam, a New Designer Benzodiazepine, in Oral Fluid After a Controlled Single Administration".Journal of Analytical Toxicology.42(6): e58–e60.doi:10.1093/jat/bky012.PMID29462316.
- ^Ameline A, Richeval C, Gaulier JM, Raul JS, Kintz P (February 2019). "Detection of the designer benzodiazepine flunitrazolam in urine and preliminary data on its metabolism".Drug Testing and Analysis.11(2): 223–229.doi:10.1002/dta.2480.PMID30109775.S2CID52001932.
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