GPR144

ADGRD2
Identifiers
Aliases	ADGRD2,PGR24, GPR144, adhesion G protein-coupled receptor D2
External IDs	HomoloGene:130029;GeneCards:ADGRD2;OMA:ADGRD2 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	124,478,589bp
RNA expressionpattern
	Top expressed in
	parotid gland; ; triceps brachii muscle; ; vena cava; ; right ventricle; ; dorsal motor nucleus of vagus nerve; ; pituitary gland; ; anterior pituitary; ; lateral nuclear group of thalamus; ; inferior olivary nucleus; ; cerebellar vermis;
	n/a
	More reference expression data
	More reference expression data
Orthologs
	347088
	n/a
	ENSG00000180264
	n/a
	n; a
	n/a
	NM_001161808; NM_182611; NM_001395425
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

Probable G-protein coupled receptor 144is aproteinthat in humans is encoded by theGPR144gene.^[3]^[4]This gene encodes a member of theadhesion-GPCRfamily of receptors. Family members are characterised by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.^[5]^[6]

References

^^a ^b ^cGRCh38: Ensembl release 89: ENSG00000180264–Ensembl,May 2017
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: GPR144 G protein-coupled receptor 144".
^Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002)."Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions".FEBS Lett.531(3): 407–14.doi:10.1016/S0014-5793(02)03574-3.PMID 12435584.S2CID 7449692.
^Stacey M, Yona S (2011).AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology).Berlin: Springer.ISBN 978-1-4419-7912-4.
^Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012)."A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis".EMBO J.31(6): 1364–78.doi:10.1038/emboj.2012.26.PMC3321182.PMID 22333914.

Vassilatis DK, Hohmann JG, Zeng H, et al. (2003)."The G protein-coupled receptor repertoires of human and mouse".Proc. Natl. Acad. Sci. U.S.A.100(8): 4903–8.Bibcode:2003PNAS..100.4903V.doi:10.1073/pnas.0230374100.PMC153653.PMID 12679517.
Humphray SJ, Oliver K, Hunt AR, et al. (2004)."DNA sequence and analysis of human chromosome 9".Nature.429(6990): 369–74.Bibcode:2004Natur.429..369H.doi:10.1038/nature02465.PMC2734081.PMID 15164053.
Bjarnadóttir TK, Fredriksson R, Höglund PJ, et al. (2005). "The human and mouse repertoire of the adhesion family of G-protein-coupled receptors".Genomics.84(1): 23–33.doi:10.1016/j.ygeno.2003.12.004.PMID 15203201.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000180264–Ensembl,May 2017

[2] "Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: GPR144 G protein-coupled receptor 144".

[pmid12435584-4] Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002)."Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions".FEBS Lett.531(3): 407–14.doi:10.1016/S0014-5793(02)03574-3.PMID 12435584.S2CID 7449692.

[isbn1-4419-7912-3-5] Stacey M, Yona S (2011).AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology).Berlin: Springer.ISBN 978-1-4419-7912-4.

[pmid22333914-6] Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012)."A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis".EMBO J.31(6): 1364–78.doi:10.1038/emboj.2012.26.PMC3321182.PMID 22333914.

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References

Further reading