GPR19

GPR19
Identifiers
Aliases	GPR19,G protein-coupled receptor 19
External IDs	OMIM:602927;MGI:892973;HomoloGene:4476;GeneCards:GPR19;OMA:GPR19 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	12,696,207bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	134,875,541bp
RNA expressionpattern
	Top expressed in
	testicle; ; gonad; ; Brodmann area 23; ; endothelial cell; ; middle temporal gyrus; ; primary visual cortex; ; ganglionic eminence; ; cerebellar hemisphere; ; pituitary gland; ; right hemisphere of cerebellum;
	Top expressed in
	spermatocyte; ; medial ganglionic eminence; ; spermatid; ; Rostral migratory stream; ; humerus; ; seminiferous tubule; ; zygote; ; pituitary gland; ; fibula; ; suprachiasmatic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; G protein-coupled receptor activity;
Cellular component	integral component of plasma membrane; membrane; integral component of membrane; plasma membrane; cilium;
Biological process	signal transduction; G protein-coupled receptor signaling pathway; neuropeptide signaling pathway; chemical synaptic transmission; feeding behavior;
	Sources:Amigo/QuickGO
Orthologs
	2842
	14760
	ENSG00000183150
	ENSMUSG00000032641
	Q15760
	Q61121
	NM_006143
NM_001167693; NM_001167694; NM_001167695; NM_001167696; NM_001167697;
	NM_001167699; NM_001167700; NM_008157; NM_001362048; NM_001362049; NM_001362050; NM_001362051; NM_001362052
	NP_006134
NP_001161166; NP_001161167; NP_001161168; NP_001161169; NP_001161171;
	NP_001161172; NP_032183; NP_001348977; NP_001348978; NP_001348979; NP_001348980; NP_001348981
	Wikidata
View/Edit Human	View/Edit Mouse

ProbableG-proteincoupled receptor 19is aproteinthat in humans is encoded by theGPR19gene.^[5]GPR19 has been proposed as thereceptorfor thepeptide hormone adropin.^[6]

References

^^a ^b ^cGRCh38: Ensembl release 89: ENSG00000183150–Ensembl,May 2017
^^a ^b ^cGRCm38: Ensembl release 89: ENSMUSG00000032641–Ensembl,May 2017
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: GPR19 G protein-coupled receptor 19".
^Stein, Lauren M.; Yosten, Gina L. C.; Samson, Willis K. (2016-03-15)."Adropin acts in brain to inhibit water drinking: potential interaction with the orphan G protein-coupled receptor, GPR19".American Journal of Physiology. Regulatory, Integrative and Comparative Physiology.310(6): R476–R480.doi:10.1152/ajpregu.00511.2015.ISSN 0363-6119.PMC4867374.PMID 26739651.

O'Dowd BF, Nguyen T, Lynch KR, et al. (1996)."A novel gene codes for a putative G protein-coupled receptor with an abundant expression in brain".FEBS Lett.394(3): 325–9.doi:10.1016/0014-5793(96)00901-5.PMID 8830667.S2CID 1484916.
Montpetit A, Sinnett D (1999). "Physical mapping of the G-protein coupled receptor 19 (GPR19) in the chromosome 12p12.3 region frequently rearranged in cancer cells".Hum. Genet.105(1–2): 162–4.doi:10.1007/s004390051080.PMID 10480372.
Otsuki T, Ota T, Nishikawa T, et al. (2007)."Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries".DNA Res.12(2): 117–26.doi:10.1093/dnares/12.2.117.PMID 16303743.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000183150–Ensembl,May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032641–Ensembl,May 2017

[3] "Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: GPR19 G protein-coupled receptor 19".

[6] Stein, Lauren M.; Yosten, Gina L. C.; Samson, Willis K. (2016-03-15)."Adropin acts in brain to inhibit water drinking: potential interaction with the orphan G protein-coupled receptor, GPR19".American Journal of Physiology. Regulatory, Integrative and Comparative Physiology.310(6): R476–R480.doi:10.1152/ajpregu.00511.2015.ISSN 0363-6119.PMC4867374.PMID 26739651.

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References

Further reading