GPR22

GPR22
Identifiers
Aliases	GPR22,G protein-coupled receptor 22
External IDs	OMIM:601910;MGI:1920260;HomoloGene:18420;GeneCards:GPR22;OMA:GPR22 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	107,475,684bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	31,763,946bp
RNA expressionpattern
	Top expressed in
	superior frontal gyrus; ; prefrontal cortex; ; testicle; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; anterior cingulate cortex; ; primary visual cortex; ; right frontal lobe; ; left ventricle; ; hippocampus proper;
	Top expressed in
	subiculum; ; interventricular septum; ; subdivision of hippocampus; ; Region I of hippocampus proper; ; hippocampus proper; ; dentate gyrus; ; lobe of cerebellum; ; cerebellar vermis; ; primary motor cortex; ; piriform cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptide binding; signal transducer activity; G protein-coupled receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane;
Biological process	cellular response to hormone stimulus; signal transduction; response to peptide; G protein-coupled receptor signaling pathway; cell projection organization;
	Sources:Amigo/QuickGO
Orthologs
	2845
	73010
	ENSG00000172209; ENSG00000283812
	ENSMUSG00000044067
	Q99680; Q3KNS9
	Q8BZL4
	NM_005295
	NM_175191
	NP_005286; NP_005286.2
	NP_780400
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 22is aproteinthat in humans is encoded by theGPR22gene.^[5]^[6]

References

^^a ^b ^cENSG00000283812 GRCh38: Ensembl release 89: ENSG00000172209, ENSG00000283812–Ensembl,May 2017
^^a ^b ^cGRCm38: Ensembl release 89: ENSMUSG00000044067–Ensembl,May 2017
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^O'Dowd BF, Nguyen T, Jung BP, Marchese A, Cheng R, Heng HH, Kolakowski LF Jr, Lynch KR, George SR (Apr 1997). "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes".Gene.187(1): 75–81.doi:10.1016/S0378-1119(96)00722-6.PMID 9073069.
^"Entrez Gene: GPR22 G protein-coupled receptor 22".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003)."Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences".Proc. Natl. Acad. Sci. U.S.A.99(26): 16899–903.Bibcode:2002PNAS...9916899M.doi:10.1073/pnas.242603899.PMC139241.PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003)."Human chromosome 7: DNA sequence and biology".Science.300(5620): 767–72.Bibcode:2003Sci...300..767S.doi:10.1126/science.1083423.PMC2882961.PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003)."The DNA sequence of human chromosome 7".Nature.424(6945): 157–64.Bibcode:2003Natur.424..157H.doi:10.1038/nature01782.PMID 12853948.
Ota T, Suzuki Y, Nishikawa T, et al. (2004)."Complete sequencing and characterization of 21,243 full-length human cDNAs".Nat. Genet.36(1): 40–5.doi:10.1038/ng1285.PMID 14702039.
Lee J, Hever A, Willhite D, et al. (2006)."Effects of RNA degradation on gene expression analysis of human postmortem tissues".FASEB J.19(10): 1356–8.doi:10.1096/fj.04-3552fje.PMID 15955843.S2CID 3200625.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006)."Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes".Genome Res.16(1): 55–65.doi:10.1101/gr.4039406.PMC1356129.PMID 16344560.

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