Girisopam
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Formula | C18H17ClN2O2 |
Molar mass | 328.80g·mol−1 |
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Girisopam[1](GYKI-51189,EGIS-5810) is a drug which is a 2,3-benzodiazepinederivative, related totofisopam[2]andzometapine.It has selectiveanxiolyticaction with nosedative,anticonvulsantormuscle relaxanteffects.[2][3][4]
See also
[edit]References
[edit]- ^US 4322346,Korosi J, Lang T, Szekely J, Andrasi F, Zolyomi G, Borsi J, Katali G, Hamori T, Gabriella S, Zsuz MN, Miglecz E, "5H-2,3-Benzodiazepine derivatives", issued 30 March 1982
- ^abAndrási F, Horváth K, Sineger E, Berzsenyi P, Borsy J, Kenessey A, Tarr M, Láng T, Kórösi J, Hámori T (October 1987). "Neuropharmacology of a new psychotropic 2,3-benzodiazepine".Arzneimittel-Forschung.37(10): 1119–24.PMID2893623.
- ^Horváth K, Andrási F, Botka P, Hámori T (1992). "Anxiolytic profile of girisopam and GYKI 52,322 (EGIS 6775). Comparison with chlordiazepoxide and buspirone".Acta Physiologica Hungarica.79(2): 153–61.PMID1363928.
- ^Horváth EJ, Salamon C, Bakonyi A, Fekete MI, Palkovits M (July 1999). "[(3)H]-girisopam, a novel selective benzodiazepine for the 2, 3-benzodiazepine binding site".Brain Research. Brain Research Protocols.4(2): 230–5.doi:10.1016/s1385-299x(99)00025-2.PMID10446419.