HDAC10
Appearance
Histone deacetylase 10is anenzymethat in humans is encoded by theHDAC10gene.[5][6][7]
Acetylation of histone core particles modulates chromatin structure and gene expression. The opposing enzymatic activities of histone acetyltransferases and histone deacetylases, such as HDAC10, determine the acetylation status of histone tails (Kao et al., 2002).[supplied by OMIM][7]
Interactions
[edit]HDAC10 has been shown tointeractwithHistone deacetylase 2[8]andNuclear receptor co-repressor 2.[8]
See also
[edit]References
[edit]- ^abcGRCh38: Ensembl release 89: ENSG00000100429–Ensembl,May 2017
- ^abcGRCm38: Ensembl release 89: ENSMUSG00000062906–Ensembl,May 2017
- ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^Kao HY, Lee CH, Komarov A, Han CC, Evans RM (Jan 2002)."Isolation and characterization of mammalian HDAC10, a novel histone deacetylase".J Biol Chem.277(1): 187–93.doi:10.1074/jbc.M108931200.PMID11677242.
- ^Guardiola AR, Yao TP (Jan 2002)."Molecular cloning and characterization of a novel histone deacetylase HDAC10".J Biol Chem.277(5): 3350–6.doi:10.1074/jbc.M109861200.PMID11726666.
- ^ab"Entrez Gene: HDAC10 histone deacetylase 10".
- ^abFischer, Denise D; Cai Richard; Bhatia Umesh; Asselbergs Fred A M; Song Chuanzheng; Terry Robert; Trogani Nancy; Widmer Roland; Atadja Peter; Cohen Dalia (Feb 2002)."Isolation and characterization of a novel class II histone deacetylase, HDAC10".J. Biol. Chem.277(8). United States: 6656–66.doi:10.1074/jbc.M108055200.ISSN0021-9258.PMID11739383.
Further reading
[edit]- Bonaldo MF, Lennon G, Soares MB (1997)."Normalization and subtraction: two approaches to facilitate gene discovery".Genome Res.6(9): 791–806.doi:10.1101/gr.6.9.791.PMID8889548.
- Dunham I, Shimizu N, Roe BA, et al. (1999)."The DNA sequence of human chromosome 22".Nature.402(6761): 489–95.Bibcode:1999Natur.402..489D.doi:10.1038/990031.PMID10591208.
- Fischer DD, Cai R, Bhatia U, et al. (2002)."Isolation and characterization of a novel class II histone deacetylase, HDAC10".J. Biol. Chem.277(8): 6656–66.doi:10.1074/jbc.M108055200.PMID11739383.
- Tong JJ, Liu J, Bertos NR, Yang XJ (2002)."Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain".Nucleic Acids Res.30(5): 1114–23.doi:10.1093/nar/30.5.1114.PMC101247.PMID11861901.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003)."Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences".Proc. Natl. Acad. Sci. U.S.A.99(26): 16899–903.Bibcode:2002PNAS...9916899M.doi:10.1073/pnas.242603899.PMC139241.PMID12477932.
- Rodriguez M, Yu X, Chen J, Songyang Z (2004)."Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains".J. Biol. Chem.278(52): 52914–8.doi:10.1074/jbc.C300407200.PMID14578343.
- Hillman RT, Green RE, Brenner SE (2005)."An unappreciated role for RNA surveillance".Genome Biol.5(2): R8.doi:10.1186/gb-2004-5-2-r8.PMC395752.PMID14759258.
- Osada H, Tatematsu Y, Saito H, et al. (2004)."Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients".Int. J. Cancer.112(1): 26–32.doi:10.1002/ijc.20395.PMID15305372.S2CID23452893.
- Collins JE, Wright CL, Edwards CA, et al. (2005)."A genome annotation-driven approach to cloning the human ORFeome".Genome Biol.5(10): R84.doi:10.1186/gb-2004-5-10-r84.PMC545604.PMID15461802.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004)."The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)".Genome Res.14(10B): 2121–7.doi:10.1101/gr.2596504.PMC528928.PMID15489334.
External links
[edit]- HDAC10+protein,+humanat the U.S. National Library of MedicineMedical Subject Headings(MeSH)
This article incorporates text from theUnited States National Library of Medicine,which is in thepublic domain.