Jeremy Brockes

Jeremy Brockes
Born	Jeremy Patrick Brockes (1948-02-29)29 February 1948 Haslemere,Surrey,England
Relatives	Emma Brockes(niece)
Academic background
Alma mater	University of Cambridge(BA) University of Edinburgh(PhD)
Academic work
Discipline	Biochemistry
Institutions	University College London Harvard Medical School California Institute of Technology King's College London

Jeremy Patrick BrockesFRS(born 29 February 1948) is a Britishbiochemistwho worked as anMRCResearch Professor atUniversity College Londonuntil 2016.

Early life and education

Brockes was born inHaslemere,Surrey.He attendedWinchester College,and then earned a Bachelor of Arts from theUniversity of Cambridge(1969) and a PhD in molecular biology from theUniversity of Edinburgh(1972), where he studied in the laboratory of the lateKenneth MurrayandNoreen Murray.He did post-doctoral research atHarvard Medical Schoolwith Zach Hall, and atUniversity College LondonwithMartin Raff.

Career

After completing post-doctoral studies, Brockes conducted research and teaching atCalifornia Institute of Technology,King's College LondonandUniversity College London.He investigated cellular interactions in the mammalianperipheral nervous system,and the mechanisms underlying limbregenerationinsalamanders.His work on the PNS yielded a method for purification and culture of rodent Schwann cells.This led to the identification of Glial Growth Factor, an early member of theNeuregulinfamily of growth factors that are key regulators in tissues such as heart and brain, as well as the PNS. His work on limb regeneration included studies on dedifferentiation, nerve dependence of regeneration, positional identity, senescent cells, and regeneration as an evolutionary variable.

He plays chess as aFIDEandECF-rated player.

Personal life

He is the uncle of award-winning journalist and authorEmma Brockes.

Works

• Brockes JP, Fields KL, Raff MC. A surface antigenic marker for rat Schwann cells.Nature 266, 364-366 (1977).
• Lemke GE, Brockes JP. Identification and purification of glial growth factor.Journal of Neuroscience 4, 75-83 (1984)
• Brockes JP, Kintner CR. Glial Growth Factor and nerve-dependent proliferation in the regeneration blastema of urodele amphibians.Cell 45, 301-306 (1986)
• Tanaka EM, Gann AA, Gates PB, Brockes JP. Newt myotubes re-enter the cell cycle by phosphorylation of the retinoblastoma protein.J. Cell Biol.136, 155-165 (1997).
• Morais da Silva S, Gates PB, Brockes JP. The newt ortholog of CD59 is implicated in proximodistal identity during amphibian limb regeneration.Dev. Cell 3, 547-555 (2002)
• Kanu N, Imokawa Y, Drechsel DN, Williamson RA, Birkett CR, Bostock CJ, Brockes JP.Transfer of scrapie prion infectivity by cell contact in culture.Current Biology 12, 523-530 (2002)
• Kumar A, Godwin JW, Gates PB, Garza-Garcia AA, Brockes JP. Molecular basis for the nerve dependence of limb regeneration in an adult vertebrate.Science 330, 485-490 (2007).
• Yun MH, Davaapil H, Brockes JP. Recurrent turnover of senescent cells during regeneration of a complex structure.eLife May 5, (2015)
• Jeremy P. Brockes, Anoop Kumar, Cristiana P. Velloso,"Regeneration as an evolutionary variable"J Anat. 2001 Jul-Aug; 199(Pt 1–2): 3–11.
• Neuroimmunology,Plenum Press, 1982,ISBN978-0-306-40955-4.

Honours and Prizes

1985 Scientific Medal,Zoological Society of London.

1989 Elected to Membership of theEuropean Molecular Biology Organisation

1989 Elected to Membership of theAcademia Europaea

1994 Elected to Fellowship of theRoyal Society

2008Newcomb Cleveland Prize(joint recipient),AAAS

2022 Inaugural Lifetime Achievement Award,International Society for Regenerative Biology

External links

• CDB Symposium 2004
• International Society for Regenerative Biology