Mucin 6

MUC6
Identifiers
Aliases	MUC6,MUC-6, mucin 6, oligomeric mucus/gel-forming
External IDs	OMIM:158374;MGI:2663233;HomoloGene:18768;GeneCards:MUC6;OMA:MUC6 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	1,036,718bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	141,655,319bp
RNA expressionpattern
	Top expressed in
	body of pancreas; ; duodenum; ; body of stomach; ; gallbladder; ; fundus; ; sural nerve; ; islet of Langerhans; ; right lobe of liver; ; right uterine tube; ; canal of the cervix;
	Top expressed in
	duodenum; ; stomach; ; neural layer of retina; ; cerebellum; ; tail of embryo; ; skeletal muscle tissue; ; cerebellar cortex; ; human kidney; ; bone marrow; ; granulocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	extracellular matrix structural constituent;
Cellular component	Golgi lumen; extracellular region; plasma membrane;
Biological process	maintenance of gastrointestinal epithelium; O-glycan processing; stimulatory C-type lectin receptor signaling pathway;
	Sources:Amigo/QuickGO
Orthologs
	4588
	353328
	ENSG00000283350; ENSG00000277281; ENSG00000184956; ENSG00000277518
	ENSMUSG00000048191
	Q6W4X9
	Q80T03; Q0VAV1
	NM_005961
	NM_181729; NM_001330001; NM_001368953
	NP_005952
	NP_859418.1; NP_001316930; NP_001355882
	Wikidata
View/Edit Human	View/Edit Mouse

Mucin 6, oligomeric mucus/gel-forming,also known asMUC6,is ahuman geneencoding a protein of the same name.^[5]MUC6, along with MUC2, MUC5AC, and MUC5B, is located within the 11p15 chromosomal locus of chromosome 11. MUC6, along with MUC1, is expressed in normal pancreases.^[6]

References

^^a ^b ^cENSG00000277281, ENSG00000184956, ENSG00000277518 GRCh38: Ensembl release 89: ENSG00000283350, ENSG00000277281, ENSG00000184956, ENSG00000277518–Ensembl,May 2017
^^a ^b ^cGRCm38: Ensembl release 89: ENSMUSG00000048191–Ensembl,May 2017
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: MUC6 mucin 6, oligomeric mucus/gel-forming".
^Monges GM, Mathoulin-Portier MP (2005). "Role of Mucins in Pancreatic Carcinoma".Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas.3:351–356.doi:10.1016/S1874-5784(05)80040-6.ISBN 978-0-12-088404-9.

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[refGRCh38Ensembl-1] ENSG00000277281, ENSG00000184956, ENSG00000277518 GRCh38: Ensembl release 89: ENSG00000283350, ENSG00000277281, ENSG00000184956, ENSG00000277518–Ensembl,May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000048191–Ensembl,May 2017

[3] "Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: MUC6 mucin 6, oligomeric mucus/gel-forming".

[6] Monges GM, Mathoulin-Portier MP (2005). "Role of Mucins in Pancreatic Carcinoma".Handbook of Immunohistochemistry and in Situ Hybridization of Human Carcinomas.3:351–356.doi:10.1016/S1874-5784(05)80040-6.ISBN 978-0-12-088404-9.

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