NS-398
Appearance
Names | |
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Preferred IUPAC name
N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
DrugBank | |
PubChemCID
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CompTox Dashboard(EPA)
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Properties | |
C13H18N2O5S | |
Molar mass | 314.36g·mol−1 |
Appearance | Off-white solid |
Insoluble | |
SolubilityinDMSO | 5 mg/mL |
Hazards | |
GHSlabelling:[1] | |
Warning | |
H302,H312,H332 | |
P280 | |
Except where otherwise noted, data are given for materials in theirstandard state(at 25 °C [77 °F], 100 kPa).
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NS-398is aCOX-2 inhibitorused in the study of the function ofcyclooxygenases.[2]
See also[edit]
- Celecoxib
- Tilmacoxib(JTE-522)
References[edit]
- ^"N194 NS-398".Sigma-Aldrich.Retrieved13 December2021.
- ^Wei Shen; Yong Li; Ying Tang; James Cummins; Johnny Huard (2005)."NS-398, a Cyclooxygenase-2-Specific Inhibitor, Delays Skeletal Muscle Healing by Decreasing Regeneration and Promoting Fibrosis".American Journal of Pathology.167(4): 1105–1117.doi:10.1016/S0002-9440(10)61199-6.PMC1603662.PMID16192645.