Normustine
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| Other names | Bis(2-chloroethyl)carbamic acid |
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| Formula | C5H9Cl2NO2 |
| Molar mass | 186.03g·mol−1 |
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Normustine,also known asbis(2-chloroethyl)carbamic acid,is anitrogen mustardandalkylating antineoplastic agent(i.e.,chemotherapy agent).[1][2][3]It is ametaboliteof a number ofantineoplastic agentsthat have been developed for the treatment oftumors,includingestramustine phosphate,alestramustine,cytestrol acetate,andICI-85966(stilbostat), but only the former of which has actually been marketed.[1][2][3]
References[edit]
- ^abBrunton L, Chabner B, Knollman B (14 January 2011).Goodman and Gilman's The Pharmacological Basis of Therapeutics, Twelfth Edition.McGraw Hill Professional. p. 1709.ISBN978-0-07-176939-6.
- ^abFox BW, Fox M (6 December 2012).Antitumor Drug Resistance.Springer Science & Business Media. pp. 199–.ISBN978-3-642-69490-5.
- ^abDecker M (5 April 2017).Design of Hybrid Molecules for Drug Development.Elsevier Science. pp. 201–.ISBN978-0-08-101118-8.
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