Alphenal
(Redirected fromPhenallymal)
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| Other names | 5-Phenyl-5-allylbarbituric acid |
| Routes of administration | Oral |
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| ECHA InfoCard | 100.003.718 |
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| Formula | C13H12N2O3 |
| Molar mass | 244.250g·mol−1 |
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Alphenal(Alphenal,Efrodal,Prophenal,Sanudorm), also known as5-allyl-5-phenylbarbituric acid,is abarbituratederivative developed in the 1920s.[1]It has primarilyanticonvulsantproperties, and was used occasionally for the treatment ofepilepsyorconvulsions,although not as commonly, as better known barbiturates such asphenobarbital.[2][3] [4][5]
LD50:Mouse (Oral): 280 mg/kg
References
[edit]- ^DE 526854,"Verfahren zur Darstellung von C,C-disubstituierten Barbitursaeuren", issued 11 June 1931, assigned to Hoffmann La Roche
- ^Carissimi M (1962). "Nuovi Barbiturici Alogenati Farmaco".Ediozione Scientifica.17(6): 390–413.
- ^Martin JR, Godel T, Hunkeler W, Jenck F, Moreau JL, Sleight AJ, Widmer U (December 2000). "Psychopharmacological Agents".Kirk-Othmer Encyclopedia of Chemical Technology.doi:10.1002/0471238961.1619250313011820.a01.ISBN0471238961.
- ^Brandenberger H, Maes RA (1997).Analytical Toxicology: For Clinical, Forensic, and Pharmaceutical Chemists.Walter de Gruyter. p. 348.ISBN978-3-11-010731-9.Retrieved19 May2012.
- ^García PC, Cruz SV, Mirón CE (28 January 2005).Fundamentos de síntesis de fármacos.Edicions Universitat Barcelona. p. 161.ISBN978-84-475-2876-9.Retrieved19 May2012.
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