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Mandible

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Mandible
Position of the mandible
Animation of the mandible
Details
PrecursorFirstpharyngeal arch[1]
Identifiers
Latinmandibula
MeSHD008334
Anatomical terms of bone

Injawed vertebrates,themandible(from theLatinmandibula,'for chewing'),lower jaw,orjawboneis abonethat makes up the lower – and typically more mobile – component of themouth(the upperjawbeing known as themaxilla).

The jawbone is theskull's only movable, posable bone, sharingjointswith the cranium'stemporal bones.The mandible hosts the lowerteeth(their depth delineated by thealveolar process). Many muscles attach to the bone, which also hostsnerves(some connecting to the teeth) andblood vessels.Amongst other functions, the jawbone is essential forchewingfood.

Owing to theNeolithic advent of agriculture(c. 10,000BCE), human jawsevolvedto besmaller.Although it is the strongest bone of thefacial skeleton,the mandible tends to deform in old age; it is also subject tofracturing.Surgery allows for the removal of jawbone fragments (or its entirety) as well as regenerative methods. Additionally, the bone is of greatforensicsignificance.

Structure

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In humans,the mandible is the largest and lowest bone in thefacial skeleton.[2]It is the only movable bone of theskull(discounting the vibratingossiclesof themiddle ear).[3]It is connected to the skull'stemporal bonesby thetemporomandibular joints.In addition to simply opening and closing, the jawbone can articulate side to side as well as forward and back.[4]

Components

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The mandible consists of:

Body

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Front view
Left side

The body of the mandible is curved, and the front part gives structure to thechin.It has two surfaces and two borders. From the outside, the mandible is marked in the midline by a faint ridge, indicating themandibular symphysis,the line of junction of the two halves of the mandible.[6]This ridge divides below and encloses a triangular eminence, themental protuberance(the chin), the base of which is depressed in the center but raised on both sides to form themental tubercle.Just above this, on both sides, thementalismuscles attach to a depression called theincisive foramen.[6]Vertically midway on either side of the body, below the secondpremolartooth, is themental foramen,through which themental nerveandblood vesselspass.[6]Running backward and upward from each mental tubercle is a faint ridge, the oblique line, which is continuous with the anterior border of the ramus.[6]Attached to this is themasseter muscle(related to mastication), thedepressor labii inferiorisanddepressor anguli oris(which support themouth), and theplatysma(extending down over much of theneck).[6]

From the inside, the mandible appears concave. On either side of the lower symphysis is themental spine(which can be faint or fused into one), to which thegenioglossus(the inferior muscle of thetongue) attaches; thegeniohyoid muscleattaches to the lower mental spine. Above the mental spine, a median foramen and furrow can line the symphysis. Below the mental spine is an oval depression (thedigastric fossa of the mandible) where thedigastric muscleattaches.[7]Extending backward and upward on either side from the lower symphysis is a ridge called themylohyoid line,where themylohyoid muscleattaches; a small part of thesuperior pharyngeal constrictor muscleattaches to the posterior ridge, near thealveolar margin.Above the anterior ridge, thesublingual glandrests against a smooth triangular area, and below the posterior ridge, thesubmandibular glandrests in an oval depression.

Medial surface of the right body and ramus, the latter penetrated by themandibular foramen(right)
Borders
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  • The superior or alveolar border, wider behind than in front, is hollowed into cavities, for the reception of the teeth; these cavities are sixteen in number and vary in depth and size according to the teeth which they contain. To the outer lip of the superior border, on either side, thebuccinatoris attached as far forward as thefirst molartooth.
  • The inferior border is rounded, longer than the superior, and thicker in front than behind; at the point where it joins the lower border of the ramus a shallow groove; for thefacial artery,may be present.

Ramus

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Themedialandlateral pterygoid musclesattach to the ramus (partlycut away,along with thecheekbone).

The ramus of the human mandible has four sides, two surfaces, four borders, and two processes. On the outside, the ramus is flat and marked by oblique ridges at its lower part. It gives attachment throughout nearly the whole of its extent to the masseter muscle.[8]

On the inside at the center there is an obliquemandibular foramen,for the entrance of theinferior alveolar vesselsandnerve.[6]The margin of this opening is irregular; it presents in front a prominent ridge, surmounted by a sharp spine, thelingula of the mandible,which gives attachment to thesphenomandibular ligament;at its lower and back part is a notch from which the mylohyoid groove runs obliquely downward and forward, and lodges themylohyoid vesselsand nerve.[6]Behind this groove is a rough surface, for the insertion of themedial pterygoid muscle.Themandibular canalruns obliquely downward and forward in the ramus, and then horizontally forward in the body, where it is placed under thealveoli,with small openings for nerves.[6]On arriving at theincisor teeth,it turns back to communicate with the mental foramen, giving off two small canals which run to the cavities containing the incisor teeth. In the posterior two-thirds of the bone the canal is situated nearer the internal surface of the mandible; and in the anterior third, nearer its external surface. It contains the inferior alveolar vessels and nerve, from which branches are distributed to the teeth.

Borders
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  • The lower border of the ramus is thick, straight, and continuous with the inferior border of the body of the bone. At its junction with the posterior border is the angle of the mandible, which may be either inverted or everted and is marked by rough, oblique ridges on each side, for the attachment of the masseter laterally, and the medial pterygoid muscle medially; thestylomandibular ligamentis attached to the angle between these muscles. The anterior border is thin above, thicker below, and continuous with the oblique line.[5]
  • The region where the lower border meets the posterior border is the angle of the mandible.
  • The posterior border is thick, smooth, rounded, and covered by theparotid gland.The upper border is thin, and is surmounted by two processes, the coronoid in front and the condyloid behind, separated by a deep concavity, themandibular notch.[5]
Processes
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  • Thecoronoid processis a thin, triangular eminence, which is flattened from side to side and varies in shape and size.
  • Thecondyloid processis thicker than the coronoid, and consists of two portions: the mandibular condyle, and the constricted portion which supports it, the neck. The condyle is the most superior part of the mandible and is part of the temporomandibular joint.[6]
  • The mandibular notch, separating the two processes, is a deep semilunar depression and is crossed by themassetericvessels and nerve.
German illustration with jawbones cut away to show theinferior alveolar nervebranching to the mandible'sdental alveoliand passing through themental foramen

Foramina

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The mandible has two main holes (foramina), found on both its left and right sides:

  • The mandibular foramen, is above the mandibular angle in the middle of each ramus.
  • The mental foramen sits on either side of the mental protuberance (chin) on the body of mandible, usually inferior to theapicesof the mandibular first and second premolars. As mandibular growth proceeds in young children, the mental foramen alters in direction of its opening from anterior to posterosuperior. The mental foramen allows the entrance of the mental nerve and blood vessels into the mandibular canal.[9]

Nerves

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Theinferior alveolar nerve(IAN), a branch of themandibular nerve(itself a major division of the cranium'strigeminal nerve), enters the mandibular foramen and runs forward in the mandibular canal, supplying sensation to thegumsand teeth.[10]Before passing through the mental foramen, the nerve divides into two terminal branches: incisive and mental nerves. The incisive nerve runs forward in the mandible and supplies the anterior teeth. The mental nerve exits the mental foramen and supplies sensation to the chin and lower lip.[10]

Variation

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Males generally have squarer, stronger, and larger mandibles than females. The mental protuberance is more pronounced in males but can be visualized and palpated in females.[citation needed]

Rarely, a bifid IAN may be present, resulting in a second and more inferiorly placed mandibular foramen. This can be detected by noting a doubled mandibular canal via radiograph.[9]

Illustration showing jaw's basic range of motion

Function

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The mandible forms the lower jaw and holds the lower teeth in place. It articulates with the left and right temporal bones at the temporomandibular joints.

The condyloid process, the superior (upper) and posterior projection from the ramus, makes the temporomandibular joint with the temporal bone. The coronoid process, superior and anterior projection from the ramus. This provides attachment to thetemporal muscle.

Teeth sit in the upper part of the body of the mandible. The frontmost part of teeth is more narrow and holds front teeth. The back part holds wider and flatter (albeit grooved) teeth primarily forchewingfood.[11] The wordmandiblederives from the Latin wordmandibula'jawbone' (literally, 'used for chewing'), frommandere'to chew' and-bula(instrumentalsuffix).

In addition to mastication, the joint of the jawbone enables actions suchspeechandyawning,[12]while playing a more subtle role in activities such askissingandbreathing.[13]

Phylogeny

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The mandible of vertebrates evolved fromMeckel's cartilage,left and right segments ofcartilagewhich supported the anteriorbranchial archin earlyfish.[14]Fish jawssurface in species of the largearthrodiregenusDunkleosteus(fl. 382–358million years ago), which crushed prey with their quickly articulating mouths.[15]The lower jaw ofcartilaginous fish,such assharks,is composed of a cartilagenous structure homologous with Meckel's cartilage. This also remains a significant element of the jaw in some primitive bony fish, such assturgeons.[16]Inreptiles,Meckel's cartilageossifiesinto the (multiple) bones of the lower jaw, while mammals of theCretaceous(145–66 Mya) had both Meckel's cartilage and a mandible.[17]

Sperm whalemandible

Inlobe-finned fishesand the early fossiltetrapods,the bonehomologousto the mandible of mammals is merely the largest of several bones in the lower jaw. In such animals, it is referred to as thedentarybone oros dentale,and forms the body of the outer surface of the jaw. It is bordered below by a number ofsplenialbones, while the angle of the jaw is formed by a lowerangular boneand asuprangularbone just above it. The inner surface of the jaw is lined by a prearticular bone, while thearticular boneforms the articulation with the skull proper. A set of three narrowcoronoid boneslie above the prearticular bone. As the name implies, the majority of the teeth are attached to the dentary, but there are commonly also teeth on the coronoid bones, and sometimes on the prearticular.[16]

Most vertebrates exhibit a simpler scheme, as bones have either fused or vanished. Inteleosts,only the dentary, articular, andangularbones remain, while in livingamphibians,the dentary is accompanied only by the prearticular, and, insalamanders,one of the coronoids. The lower jaw of reptiles has only a single coronoid and splenial, but retains all the other primitive bones except the prearticular and the periosteum.[16]In birds, the various bones have fused into a single structure. In mammals, most have disappeared, leaving only the mandible. As a result, there is only articulation between the mandible and temporal bones, as opposed to articulation between articular andquadrate bones.An intermediate stage can be seen in sometherapsids,in which both points of articulation are present. Aside from the dentary, only few other bones of the lower jaw remain in mammals; the former articular and quadrate bones survive as themalleusand theincusof the middle ear.[16]

In recenthuman evolution,both the oral cavity andjaws have shrunkin correspondence with theNeolithic-era shiftfromhunter-gathererlifestyles towardsagricultureand settlement, dated toc. 10,000BCE.[18][19][20][21]This has led to orthodonticmalocclusions.[18]

Development

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The mandible forms as a bone (ossifies) from Meckel's cartilage, which forms the cartilaginous bar of themandibular archand, dorsally, parts of the middle ear.[14]The two sides of the jawbone are inferiorly fused at the mandibular symphysis (the chin) during the first year of life.[6]The cartilage of the ramus is replaced by fibrous tissue, which persists to form thesphenomandibular ligament.[5]Between the lingula and the canine tooth the cartilage disappears, while the portion of it below and behind the incisor teeth becomes ossified and incorporated with this part of the mandible.[5]

About the sixth week of fetal life,intramembranous ossificationtakes place in the membrane covering the outer surface of the ventral end of Meckel's cartilage, and each half of the bone is formed from a single center which appears, near the mental foramen.[5]By the tenth week, the portion of Meckel's cartilage which lies below and behind the incisor teeth is surrounded and invaded by thedermal bone(also known as the membrane bone). Somewhat later, accessory nuclei of cartilage make their appearance, as

  • a wedge-shaped nucleus in the condyloid process and extending downward through the ramus;
  • a small strip along the anterior border of the coronoid process;
  • smaller nuclei in the front part of both alveolar walls and along the front of the lower border of the bone.[5]

These accessory nuclei possess no separate ossific centers but are invaded by the surrounding dermal bone and undergo absorption. The inner alveolar border, usually described as arising from a separate ossific center (splenialcenter), is formed in the human mandible by an ingrowth from the main mass of the bone.[5]

Embryonic development, right side

Aging

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At birth, the body of the bone is a mere shell, containing the sockets of the two incisor, the canine, and the two deciduousmolar teeth,imperfectly partitioned off from one another. The mandibular canal is of large size and runs near the lower border of the bone; the mental foramen opens beneath the socket of the first deciduous molar tooth. The angle is obtuse (175°), and the condyloid portion is nearly in line with the body. The coronoid process is of comparatively large size, and projects above the level of the condyle.[5]

After birth, the two segments of the bone become joined at the symphysis, from below upward, in the first year; but a trace of separation may be visible in the beginning of the second year, near the alveolar margin. The body becomes elongated in its whole length, but more especially behind the mental foramen, to provide space for the three additional teeth developed in this part. The depth of the body increases owing to increased growth of the alveolar part, to afford room for the roots of the teeth, and by thickening of the subdental portion which enables the jaw to withstand the powerful action of the masticatory muscles; but, the alveolar portion is the deeper of the two, and, consequently, the chief part of the body lies above the oblique line. The mandibular canal, after the second dentition, is situated just above the level of themylohyoid line;and the mental foramen occupies the position usual to it in the adult. The angle becomes less obtuse, owing to the separation of the jaws by the teeth; about the fourth year it is 140°.[5]Thefibrocartilageof the mandibular symphysis fuses together in early childhood.[9]

In the adult, the alveolar and subdental portions of the body are usually of equal depth. The mental foramen opens midway between the upper and lower borders of the bone, and the mandibular canal runs nearly parallel with the mylohyoid line. The ramus is almost vertical in direction, the angle measuring from 110° to 120°, also the adult condyle is higher than the coronoid process and the sigmoid notch becomes deeper.[5]The adult mandible is the skull's largest and strongest bone.[2]

In old age, the bone can become greatly reduced in volume where there is a loss of teeth, and consequent resorption of the alveolar process and interalveolar septa. Consequently, the chief part of the bone is below the oblique line. The mandibular canal, with the mental foramen opening from it, is closer to the alveolar border. The ramus is oblique in direction, the angle measures about 140°, and the neck of the condyle is more or less bent backward.[5]

Clinical significance

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The posterior of the mandible is notoriously resistant to the full effects of localanesthesia.The IAN providessensory innervationto much of the mandible and its teeth, making it a target ofblock anesthesia.Injecting the nerve is challenging due to the amount of surroundingsoft tissue.American surgeonWilliam Stewart Halsteddeveloped a technique using asyringeandcocainewhich was performed successfully by 1885.[22]

Fracture

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Fracture frequency by location[23]

One fifth offacial injuriesinvolve a mandibular fracture.[24]Mandibular fractures are often accompanied by a 'twin fracture' on the opposite side. There is no universally accepted treatment protocol, as there is no consensus on the choice of techniques in a particular anatomical shape of mandibular fracture clinic. A common treatment involves attachment of metal plates to the fracture to assist in healing.[citation needed]

Causes of mandibular fractures[23]
Cause Percentage
Motor vehicle accident 40%
Assault 10%
Fall 10%
Sport 5%
Other 5%

Dislocation and displacement

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The mandible may bedislocatedanteriorly (to the front) and inferiorly (downwards) but very rarely posteriorly (backwards). Thearticular disk of the temporomandibular jointprevents the mandible from moving posteriorly, making the condylar neck particularly vulnerable to fractures.[6]Further, various jawbone damage can causetemporomandibular joint dysfunction,with symptoms including pain andinflammation.[12]

The jawbone can also become deviated inmandibular lateral displacement,a condition which can offsetfacial symmetryand cause posteriorcrossbite.[25]

Resorption

[edit]

The mandibular alveolar process can become resorbed when completely edentulous in the mandibular arch (occasionally noted also in partially edentulous cases). This resorption can occur to such an extent that the mental foramen is virtually on the superior border of the mandible, instead of opening on the anterior surface, changing its relative position. However, the more inferior body of the mandible is not affected and remains thick and rounded. With age and tooth loss, the alveolar process is absorbed so that the mandibular canal becomes nearer the superior border. Sometimes with excessive alveolar process absorption, the mandibular canal disappears entirely and deprives the IAN of its bony protection, although soft tissue continues to guard the nerve.[9]

Mandibulectomy

[edit]

The surgical removal (resection) of all or part of the jawbone is known as amandibulectomy.[26]The removal of a small portion is known aspartial mandibulectomyand a larger portionsegmental mandibulectomy.This can be performed to remove a tumor, circumvent cancer in nearby areas, and/or in response to infection,osteonecrosis,or injury.[27]The removed portion can be replaced with metal plating or bone from elsewhere in the body. Oral muscles tend to work differently after the procedure, requiring therapy to relearn operations such as eating and speaking. During recovery, afeeding tubeis utilized, and sometimes atracheotomyis also performed tomaintain respirationin case of swollen muscles.[28]In a technique illustrated in the 19th century, the flesh of the face is incised along the inferior of the mandible and peeled upward for the bone's removal.[29]

Complications can involve difficulties withfree flaptransfer and airway management.[30][31]Additional side effects include pain, infection, numbness, and (rarely, fatal) bleeding.[32]Even successful surgeries can result indeformity,with an extreme version being referred to as theAndy Gump deformityafterthe comic book character,whose design apparently lacks a jaw; proposed reconstruction methods include implantingsynthetic material,potentially involving3D printing.[33]

Dental implantssupportingfalse teeth

Regeneration

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Bone loss (as inosteoporosis) can be mitigated in the jawbone viabone grafting,which is sometimes performed to supportdental implants(replacing teeth individually orin groups).[34]

Mandibular prosthetics date back toancient EgyptandChina,but significant advancements were made in the late 19th century with new techniques for attaching prosthetics to a depreciated jawbone as well as bone grafting.[35]

In 2010, the first successfulface transplantwas conducted on a Spanish farmer after a self-inflictedgun accident;this included the replacement of the entire mandible.[36]

Forensic medicine

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The mandible can provide forensic evidence because its form changes over a person's life, and this can be used to determine a deceased person's age.[6]

Dental remains ofNazileaderAdolf Hitler,including part of a mandible with teeth, were the solitary physical evidence used to confirmhis deathin 1945.[37]

In culture

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In theHebrew Bibleand Christian Old TestamentBook of Judges,Samsonused a donkey's jawbone to kill a thousandPhilistines.[38]

As early as 1900, the phrasejaw-droppingwas used as an adjective to describe a condition of shock in humans, e.g. when someone's mouth suddenly hangs agape in response to something. The exaggeratedvisual gagof a jaw dropping to the floor was a trademark of American animation directorTex Avery,who would often employ it when theBig Bad Wolfspies asexually attractivewoman.[39]

Gobstoppers,a type of hard candy, are known in North America asjawbreakersdue to the fracturing risk they impose on teeth.[40]

Owing in part to the forensic evidence of Hitler's death being limited to his dental remains (including a jawbone fragment broken and burnt around the alveolar process),[41]some fringe accounts (bolstered by theSoviet Union,which captured Berlin in 1945) allege thatHitler faked his death(ostensibly along withEva Braun).[37]

In later decades, American real-estate businessmanFred Trumphad a partial mandibulectomy which caused a conspicuous deformity.[42][43]In his fight against cancer, American film criticRoger Eberthad a partial mandibulectomy in 2006,[44]in addition to later surgeries.[36]

Additional images

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See also

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References

[edit]

Public domainThis article incorporates text in thepublic domainfrompage 172of the 20th edition ofGray's Anatomy(1918)

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  31. ^Kwon, Min A.; Song, Jaegyok; Kim, Seokkon; Oh, Pyeung-wha; Kang, Minji (2021)."Airway Management Failure after Delayed Extubation in a Patient with Oral Malignant Melanoma Who Underwent Partial Mandibulectomy and Reconstruction with a Free Flap".Case Reports in Dentistry.2021:1–5.doi:10.1155/2021/7792843.PMC8716215.PMID34976416.
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  36. ^abEbert, Roger (6 May 2010)."Putting a better face on things".Roger Ebert.Retrieved29 November2023.
  37. ^abJoachimsthaler, Anton(1998) [1996].The Last Days of Hitler.London:Arms & Armour Press.pp. 180, 225.ISBN978-1-85409-465-0.
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  41. ^Charlier, Philippe;Weil, Raphael; Rainsard, P.; Poupon, Joël; Brisard, J. C. (1 May 2018)."The remains of Adolf Hitler: A biomedical analysis and definitive identification".European Journal of Internal Medicine.54:e10–e12.doi:10.1016/j.ejim.2018.05.014.PMID29779904.S2CID29159362.It is important to see that these data fit perfectly withthe [Soviet] autopsy reportand with our direct observations.
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